Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNA3 | P22001 | 1/20 | 0.75 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.58 |
| ▸ | RECQL | P46063 | 1/20 | 0.58 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.58 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.58 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.58 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.58 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.58 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.58 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.58 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.58 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.58 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.58 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.58 |
| ▸ | DRD2 | P14416 | 1/20 | 0.58 |
| ▸ | DRD4 | P21917 | 1/20 | 0.58 |
| ▸ | DRD3 | P35462 | 1/20 | 0.58 |
| ▸ | LTA4H | P09960 | 3/20 | 0.56 |
| ▸ | HTR1B | P28222 | 2/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9011603 | 0.95 | KCNA3 (0.84) | KCNA3TAAR1ALDH1A1RECQLHDAC3 | |
| SCHEMBL14097361 | 0.95 | KCNA3 (0.84) | KCNA3TAAR1ALDH1A1RECQLHDAC3 | |
| SCHEMBL1025 | 0.92 | KCNA3 (0.88) | KCNA3TAAR1ALDH1A1RECQLHDAC3 | |
| SCHEMBL5175295 | 0.89 | KCNA3 (0.60) | KCNA3TAAR1ALDH1A1RECQLHDAC3 | |
| SCHEMBL22266160 | 0.89 | KCNA3 (0.60) | KCNA3TAAR1ALDH1A1RECQLHDAC3 | |
| SCHEMBL11420388 | 0.89 | KCNA3 (0.60) | KCNA3TAAR1ALDH1A1RECQLHDAC3 | |
| SCHEMBL972461 | 0.89 | ALDH1A1 (0.65) | KCNA3TAAR1ALDH1A1RECQLHDAC3 | |
| SCHEMBL10390291 | 0.89 | ALDH1A1 (0.72) | KCNA3TAAR1ALDH1A1RECQLHDAC3 | |
| SCHEMBL5173415 | 0.89 | ALDH1A1 (0.65) | KCNA3TAAR1ALDH1A1RECQLHDAC3 | |
| SCHEMBL3369424 | 0.89 | LTA4H (0.62) | KCNA3TAAR1ALDH1A1RECQLHDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9242955-B2 | Synthesis of cyclic carbonates | UNIVERSITY OF YORK (GB) | 2016-01-26 | — | — | US | disclosed |
| CN-101679343-B | Synthesis of cyclic carbonates in the presence of dimeric aluminium (salen) catalysts | UNIV NEWCASTLE | 2014-06-18 | — | — | CN | disclosed |
| EP-2146977-B1 | SYNTHESIS OF CYCLIC CARBONATES IN THE PRESENCE OF DIMERIC ALUMINIUM (SALEN) CATALYSTS | UNIV NEWCASTLE (GB) | 2012-11-14 | — | — | EP | disclosed |
| US-20100130752-A1 | SYNTHESIS OF CYCLIC CARBONATES | UNIVERSITY OF NEWCASTLE UPON TYNE (GB) | 2010-05-27 | — | — | US | disclosed |
| CN-101679343-A | Synthesis of cyclic carbonates in the presence of dimeric aluminium (salen) catalysts | UNIV NEWCASTLE | 2010-03-24 | — | — | CN | disclosed |
| EP-2146977-A1 | SYNTHESIS OF CYCLIC CARBONATES IN THE PRESENCE OF DIMERIC ALUMINIUM (SALEN) CATALYSTS | University Of Newcastle-Upon Tyne (GB) | 2010-01-27 | — | — | EP | disclosed |
| WO-2008132474-A1 | SYNTHESIS OF CYCLIC CARBONATES IN THE PRESENCE OF DIMERIC ALUMINIUM (SALEN) CATALYSTS | UNIVERSITY OF NEWCASTLE UPON TYNE (GB) | 2008-11-06 | — | — | WO | disclosed |
| US-20030229113-A1 | Keratinocyte growth inhibitors and hydroxamic acid derivatives | AKZO NOBEL N.V. (NL) | 2003-12-11 | — | — | US | disclosed |
| EP-0025528-B1 | 1-(2-ACETYLPHENYLTHIO)-3-ALKYLAMINO-2-PROPANOLS AND THEIR ACID-ADDITION SALTS, PROCESS FOR THEIR PREPARATION AND MEDICINES CONTAINING THEM | A. Nattermann & Cie. GmbH (DE) | 1982-12-29 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100130752-A1 | SYNTHESIS OF CYCLIC CARBONATES | CA2, SCO2, CA7 | KCNA3 3304/4885TAAR1 3397/4885ALDH1A1 3403/4885 |
| US-20030229113-A1 | Keratinocyte growth inhibitors and hydroxamic acid derivatives | FGF1, FGF2, EGFR | KCNA3 2951/4885TAAR1 4113/4885ALDH1A1 2165/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.