Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | CDK1 | P06493 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 5/20 | 0.41 |
| ▸ | CA1 | P00915 | 3/20 | 0.38 |
| ▸ | CA9 | Q16790 | 3/20 | 0.38 |
| ▸ | CA5A | P35218 | 1/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 2/20 | 0.37 |
| ▸ | CA7 | P43166 | 2/20 | 0.37 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.37 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.37 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9724720 | 0.87 | CA2 (0.46) | KDM4EALDH1A1HSD17B10MAPTHPGD | |
| SCHEMBL20887338 | 0.75 | CA12 (0.66) | KDM4EALDH1A1HSD17B10MAPTHPGD | |
| SCHEMBL23292500 | 0.74 | HPGD (0.54) | KDM4EALDH1A1HSD17B10MAPTHPGD | |
| SCHEMBL26466965 | 0.74 | ALDH1A1 (0.76) | KDM4EALDH1A1HSD17B10MAPTHPGD | |
| SCHEMBL17478646 | 0.74 | HPGD (0.49) | KDM4EALDH1A1HSD17B10MAPTHPGD | |
| SCHEMBL13162022 | 0.72 | CA12 (0.47) | KDM4EALDH1A1HSD17B10MAPTHPGD | |
| SCHEMBL9724767 | 0.71 | GAA (0.54) | MAPTGAACDK1TP53 | |
| SCHEMBL9724769 | 0.71 | CA2 (0.48) | KDM4EALDH1A1HSD17B10MAPTHPGD | |
| SCHEMBL13162548 | 0.71 | ALDH1A1 (0.60) | KDM4EALDH1A1HSD17B10MAPTHPGD | |
| SCHEMBL22006228 | 0.71 | CA12 (0.46) | KDM4EALDH1A1HSD17B10MAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5160363-A | For sugarbeets | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1992-11-03 | — | — | US | disclosed |
| EP-0422031-A1 | HERBICIDAL SULFONAMIDES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1991-04-17 | — | — | EP | disclosed |
| WO-1989010921-A1 | HERBICIDAL SULFONAMIDES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1989-11-16 | — | — | WO | disclosed |