Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.61 |
| ▸ | HSPA1A | P0DMV8 | 1/20 | 0.60 |
| ▸ | HSPA5 | P11021 | 1/20 | 0.60 |
| ▸ | HSPA9 | P38646 | 1/20 | 0.60 |
| ▸ | HSPA2 | P54652 | 1/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 4/20 | 0.53 |
| ▸ | TSHR | P16473 | 2/20 | 0.53 |
| ▸ | NPC1 | O15118 | 2/20 | 0.53 |
| ▸ | RAB9A | P51151 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | XBP1 | P17861 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | MME | P08473 | 4/20 | 0.52 |
| ▸ | ACE | P12821 | 3/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26502086 | 0.85 | PKM (0.65) | PKMHSPA1AHSPA5HSPA9HSPA2 | |
| SCHEMBL6170983 | 0.83 | MME (0.48) | MMEACEALDH1A1HSD17B10HPGD | |
| SCHEMBL9724929 | 0.82 | PKM (0.63) | PKMHSPA1AHSPA5HSPA9HSPA2 | |
| SCHEMBL386632 | 0.78 | MME (0.51) | L3MBTL1MMEACEALDH1A1HSD17B10 | |
| SCHEMBL7271417 | 0.76 | MME (0.65) | MMEACEALDH1A1HSD17B10HPGD | |
| SCHEMBL5097467 | 0.76 | MME (0.57) | MMEACEALDH1A1HSD17B10HPGD | |
| SCHEMBL7346217 | 0.76 | MME (0.69) | MMEACEALDH1A1HSD17B10HPGD | |
| SCHEMBL6161590 | 0.76 | MME (0.66) | MME | |
| SCHEMBL3410335 | 0.76 | MME (0.66) | MME | |
| SCHEMBL7315829 | 0.76 | MME (0.66) | MME |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5098934-A | Enkephalinase inhibitors as analgesics or anticargcinogenic agents | ROUSSEL UCLAF (FR) | 1992-03-24 | — | — | US | disclosed |