Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.63 |
| ▸ | HSPA5 | P11021 | 2/20 | 0.62 |
| ▸ | HSPA9 | P38646 | 2/20 | 0.62 |
| ▸ | HSPA1A | P0DMV8 | 1/20 | 0.62 |
| ▸ | HSPA2 | P54652 | 1/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 4/20 | 0.55 |
| ▸ | NPC1 | O15118 | 3/20 | 0.55 |
| ▸ | RAB9A | P51151 | 3/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.55 |
| ▸ | TSHR | P16473 | 2/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | XBP1 | P17861 | 1/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | ACP1 | P24666 | 1/20 | 0.54 |
| ▸ | USP2 | O75604 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26502086 | 0.85 | PKM (0.65) | PKMHSPA5HSPA9HSPA1AHSPA2 | |
| SCHEMBL9724834 | 0.82 | PKM (0.61) | PKMHSPA5HSPA9HSPA1AHSPA2 | |
| SCHEMBL23804618 | 0.77 | HSPA5 (1.00) | PKMHSPA5HSPA9HSPA1AHSPA2 | |
| SCHEMBL23804617 | 0.77 | HSPA5 (1.00) | PKMHSPA5HSPA9HSPA1AHSPA2 | |
| SCHEMBL4687548 | 0.76 | FFAR2 (0.74) | KDM4ELMNANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL7879989 | 0.75 | HSPA1A (0.58) | PKMHSPA5HSPA9HSPA1AHSPA2 | |
| SCHEMBL7879986 | 0.75 | HSPA1A (0.58) | PKMHSPA5HSPA9HSPA1AHSPA2 | |
| SCHEMBL9724808 | 0.75 | MEN1 (0.53) | LMNANPC1RAB9ACYP2D6TP53 | |
| SCHEMBL29687163 | 0.74 | HSPA5 (0.64) | PKMHSPA5HSPA9HSPA1AHSPA2 | |
| SCHEMBL6960135 | 0.74 | HSPA1A (0.60) | PKMHSPA5HSPA9HSPA1AHSPA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5098934-A | Enkephalinase inhibitors as analgesics or anticargcinogenic agents | ROUSSEL UCLAF (FR) | 1992-03-24 | — | — | US | disclosed |