Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 14/20 | 0.53 |
| ▸ | CA9 | Q16790 | 14/20 | 0.53 |
| ▸ | CA2 | P00918 | 13/20 | 0.53 |
| ▸ | CA1 | P00915 | 8/20 | 0.53 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.48 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.48 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.48 |
| ▸ | RET | P07949 | 1/20 | 0.48 |
| ▸ | PIM1 | P11309 | 1/20 | 0.48 |
| ▸ | LTK | P29376 | 1/20 | 0.48 |
| ▸ | GRK5 | P34947 | 1/20 | 0.48 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.48 |
| ▸ | CDK8 | P49336 | 1/20 | 0.48 |
| ▸ | PRKX | P51817 | 1/20 | 0.48 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.48 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.48 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.48 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.48 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.48 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8337671 | 0.75 | CHEK1 (0.54) | CA12CA9CA2CA1CHEK1 | |
| Saccharin SCHEMBL29283763 | 0.74 | CA12 (0.65) | CA12CA9CA2CA1CA7 | |
| SCHEMBL28122890 | 0.74 | RET (0.57) | CA12CA9CA2CA1CHEK1 | |
| SCHEMBL12745902 | 0.70 | CHEK1 (0.51) | CA12CA9CA2CA1CHEK1 | |
| SCHEMBL19066303 | 0.69 | CHEK1 (0.48) | CA12CA9CA2CA1CHEK1 | |
| SCHEMBL29643014 | 0.69 | CHEK1 (0.48) | CA12CA9CA2CA1CHEK1 | |
| SCHEMBL17762970 | 0.69 | MAPT (0.57) | CA2KDM4ELMNAKMT2ACYP3A4 | |
| SCHEMBL132773 | 0.69 | ALDH1A1 (0.78) | CA2KDM4ELMNAKMT2ACYP3A4 | |
| SCHEMBL32689426 | 0.69 | CHEK1 (0.62) | CA12CA9CA2CA1CHEK1 | |
| SCHEMBL1666180 | 0.69 | CHEK1 (0.62) | CA12CA9CA2CA1CHEK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5160363-A | For sugarbeets | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1992-11-03 | — | — | US | disclosed |
| EP-0422031-A1 | HERBICIDAL SULFONAMIDES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1991-04-17 | — | — | EP | disclosed |
| WO-1989010921-A1 | HERBICIDAL SULFONAMIDES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1989-11-16 | — | — | WO | disclosed |