Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHEK1 | O14757 | 1/20 | 0.62 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.62 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.62 |
| ▸ | RET | P07949 | 1/20 | 0.62 |
| ▸ | PIM1 | P11309 | 1/20 | 0.62 |
| ▸ | LTK | P29376 | 1/20 | 0.62 |
| ▸ | GRK5 | P34947 | 1/20 | 0.62 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.62 |
| ▸ | CDK8 | P49336 | 1/20 | 0.62 |
| ▸ | PRKX | P51817 | 1/20 | 0.62 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.62 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.62 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.62 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.62 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.62 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.62 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.62 |
| ▸ | NTRK3 | Q16288 | 1/20 | 0.62 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.62 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL32689426 | 1.00 | CHEK1 (0.62) | CHEK1DAPK3MAP4K4RETPIM1 | |
| SCHEMBL12745931 | 0.85 | RET (0.55) | CHEK1DAPK3MAP4K4RETPIM1 | |
| SCHEMBL29349483 | 0.85 | CA12 (0.62) | CHEK1DAPK3MAP4K4RETPIM1 | |
| SCHEMBL1249735 | 0.85 | CA12 (0.62) | CHEK1DAPK3MAP4K4RETPIM1 | |
| SCHEMBL23600959 | 0.82 | CLK4 (0.51) | CHEK1DAPK3MAP4K4RETPIM1 | |
| SCHEMBL12745929 | 0.82 | RET (0.55) | CHEK1DAPK3MAP4K4RETPIM1 | |
| SCHEMBL3984666 | 0.77 | RET (1.00) | CHEK1DAPK3MAP4K4RETPIM1 | |
| SCHEMBL2208975 | 0.77 | CHEK1 (0.62) | CHEK1DAPK3MAP4K4RETPIM1 | |
| SCHEMBL1684375 | 0.77 | CHEK1 (0.62) | CHEK1DAPK3MAP4K4RETPIM1 | |
| SCHEMBL3988311 | 0.77 | CA12 (0.73) | CHEK1DAPK3MAP4K4RETPIM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 125 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5228929-A | Thermochemical treatment of machinery components for improved corrosion resistance | PANASIUK WLADYSLAW (PL) | 1993-07-20 | — | — | US | claimed |
| EP-0534010-A1 | Thermochemical treatment of machinery components for improved corrosion resistance | NITREX METAL INC (CA) | 1993-03-31 | — | — | EP | claimed |
| US-11999758-B2 | Inhibitors of the YAP/TAZ-TEAD interaction and their use in the treatment of cancer | INVENTIVA (FR) | 2024-06-04 | — | — | US | disclosed |
| CN-113039182-B | Inhibitors of YAP/TAZ-TEAD interactions and their use in cancer treatment | 伊文蒂瓦公司 | 2024-02-20 | — | — | CN | disclosed |
| US-20230416793-A1 | METHOD OF PRODUCING L-AMINO ACID | AJINOMOTO CO., INC. (JP) | 2023-12-28 | — | — | US | disclosed |
| US-20230330305-A1 | HYDROGEL COMPRISING A CROSS-LINKED AND SILYLATED POLYSACCHARIDE AND PROCESS FOR OBTAINING SAME | Teoxane SA (CH) | 2023-10-19 | — | — | US | disclosed |
| WO-2023198920-A1 | METHOD FOR PRODUCING A HYDROGEL | Teoxane SA (CH) | 2023-10-19 | — | — | WO | disclosed |
| WO-2023198917-A1 | HYDROGELS FOR SOFT TISSUE FILLING | Teoxane SA (CH) | 2023-10-19 | — | — | WO | disclosed |
| WO-2023198922-A1 | METHOD FOR PRODUCING A HYDROGEL COMPRISING A CROSS-LINKED SILYLATED POLYSACCHARIDE | Teoxane SA (CH) | 2023-10-19 | — | — | WO | disclosed |
| EP-4239070-A1 | METHOD OF PRODUCING L-AMINO ACID | AJINOMOTO CO., INC. (JP) | 2023-09-06 | — | — | EP | disclosed |
| CN-116648147-A | Composition for premature infants to shorten the time to full enteral feeding | 雀巢产品有限公司 | 2023-08-25 | — | — | CN | disclosed |
| US-4764239-A | STORAGE STABLE ADHESIVE | LOCTITE CORPORATION (US) | 1988-08-16 | — | — | US | disclosed |
| EP-0232364-A1 | SUBSTITUTED SACCHARIN COMPOUNDS AND CURABLE COMPOSITIONS CONTAINING SAME. | LOCTITE CORP (US) | 1987-08-19 | — | — | EP | disclosed |
| WO-1987000536-A1 | SUBSTITUTED SACCHARIN COMPOUNDS AND CURABLE COMPOSITIONS CONTAINING SAME | LOCTITE CORPORATION (US) | 1987-01-29 | — | — | WO | disclosed |
| US-4490527-A | Benzo-fused heterocyclic anti-ulcer agents | AMERICAN HOME PRODUCTS CORPORATION (US) | 1984-12-25 | — | — | US | disclosed |
| US-4430355-A | ARTIFICIAL SWEETENER | DR. KARL THOMAE GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1984-02-07 | — | — | US | disclosed |
| EP-0014322-B1 | POLYCARBONATE COMPOSITION CONTAINING A METAL SALT OF AN AROMATIC SULFONAMIDE AS AN IGNITION DEPRESSANT | THE DOW CHEMICAL COMPANY (US) | 1983-01-12 | — | — | EP | disclosed |
| US-4233299-A | ANTIINFLAMMATORY AGENTS, ANTIPYRETICS | BOEHRINGER INGELHEIM GMBH (DE) | 1980-11-11 | — | — | US | disclosed |
| US-4233333-A | 4,5-Dimethyl-thieno[3,2-d]isothiazolo-3(2H)-one-1,1-dioxides, compositions, and methods of use as a sweetener | BOEHRINGER INGELHEIM GMBH (DE) | 1980-11-11 | — | — | US | disclosed |
| EP-0014322-A1 | Polycarbonate composition containing a metal salt of an aromatic sulfonamide as an ignition depressant | THE DOW CHEMICAL COMPANY (US) | 1980-08-20 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11999758-B2 | Inhibitors of the YAP/TAZ-TEAD interaction and their use in the treatment of cancer | YAP1, TEAD2, YES1 | CHEK1 125/4885DAPK3 247/4885MAP4K4 469/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.