Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCC9 | O60706 | 7/20 | 0.64 |
| ▸ | KCNE1 | P15382 | 4/20 | 0.60 |
| ▸ | KCNQ1 | P51787 | 4/20 | 0.60 |
| ▸ | MEN1 | O00255 | 1/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.60 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.60 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.60 |
| ▸ | KCND3 | Q9UK17 | 1/20 | 0.60 |
| ▸ | ABCB1 | P08183 | 7/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9724890 | 1.00 | ABCC9 (0.64) | ABCC9KCNE1KCNQ1MEN1CYP1A2 | |
| SCHEMBL9724900 | 1.00 | ABCC9 (0.64) | ABCC9KCNE1KCNQ1MEN1CYP1A2 | |
| SCHEMBL9197751 | 0.80 | ABCC9 (0.68) | ABCC9ABCB1 | |
| SCHEMBL9197759 | 0.80 | ABCC9 (0.68) | ABCC9ABCB1 | |
| SCHEMBL9197746 | 0.80 | ABCC9 (0.68) | ABCC9ABCB1 | |
| SCHEMBL9273379 | 0.80 | ABCC9 (0.78) | ABCC9ABCB1KDM4E | |
| SCHEMBL9532337 | 0.80 | ABCC9 (0.78) | ABCC9ABCB1KDM4E | |
| SCHEMBL9532318 | 0.80 | ABCC9 (0.78) | ABCC9ABCB1KDM4E | |
| SCHEMBL9273381 | 0.80 | ABCC9 (0.78) | ABCC9ABCB1KDM4E | |
| SCHEMBL9273375 | 0.80 | ABCC9 (0.78) | ABCC9ABCB1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5151442-A | Cardiovascular disorders and nervous system disorders | SANOFI (FR) | 1992-09-29 | — | — | US | disclosed |
| US-5082858-A | Antidepressants | SANOFI (FR) | 1992-01-21 | — | — | US | disclosed |