Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.36 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.35 |
| ▸ | CLCN2 | P51788 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.33 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.33 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.33 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8094464 | 0.87 | ALDH1A1 (0.38) | ALDH1A1ALOX15KMT2AMEN1TSHR | |
| SCHEMBL9724906 | 0.84 | FOLH1 (0.49) | ALDH1A1ALOX15KMT2AMEN1TSHR | |
| SCHEMBL9724910 | 0.84 | FOLH1 (0.49) | ALDH1A1ALOX15KMT2AMEN1TSHR | |
| SCHEMBL8094597 | 0.84 | ALDH1A1 (0.41) | ALDH1A1ALOX15KMT2AMEN1TSHR | |
| SCHEMBL8087714 | 0.84 | GABRA1 (0.48) | ALDH1A1ALOX15KMT2AMEN1TSHR | |
| SCHEMBL8098416 | 0.83 | ALDH1A1 (0.44) | ALDH1A1TSHRFOLH1TP53LMNA | |
| SCHEMBL8085912 | 0.83 | KMT2A (0.39) | ALDH1A1KMT2AMEN1TSHRFOLH1 | |
| SCHEMBL27700923 | 0.83 | IRAK4 (0.45) | ALDH1A1KMT2AMEN1TSHRKDM4E | |
| SCHEMBL8100828 | 0.82 | ALDH1A1 (0.46) | ALDH1A1KMT2AMEN1TSHRFOLH1 | |
| SCHEMBL8878987 | 0.81 | ALDH1A1 (0.43) | ALDH1A1KMT2AMEN1TSHRFOLH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0708077-B1 | Diamino compounds and methods for preparing them | CHISSO CORP (JP) | 2000-12-27 | — | — | EP | disclosed |
| US-5663440-A | Diamino compounds and methods for preparing them | CHISSO CORPORATION (JP) | 1997-09-02 | — | — | US | disclosed |
| EP-0708077-A1 | Diamino compounds and methods for preparing them | CHISSO CORPORATION (JP) | 1996-04-24 | — | — | EP | disclosed |