Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | MAOB | P27338 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | FPR2 | P25090 | 1/20 | 0.42 |
| ▸ | CTBP2 | P56545 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9660152 | 0.91 | MAOB (0.50) | L3MBTL1MAOBALDH1A1MAPTLMNA | |
| SCHEMBL14893201 | 0.89 | MAOB (0.50) | L3MBTL1MAOBALDH1A1MAPTLMNA | |
| SCHEMBL3849886 | 0.87 | ALDH1A1 (0.54) | L3MBTL1MAOBALDH1A1MAPTLMNA | |
| SCHEMBL28106122 | 0.85 | L3MBTL1 (0.48) | L3MBTL1MAOBALDH1A1MAPTLMNA | |
| SCHEMBL9818570 | 0.85 | GAA (0.45) | L3MBTL1ALDH1A1MAPTLMNANPC1 | |
| SCHEMBL19181 | 0.85 | CYP4F2 (0.54) | L3MBTL1MAOBALDH1A1MAPTKDM4E | |
| SCHEMBL4953662 | 0.85 | MAOB (0.47) | L3MBTL1MAOBALDH1A1MAPTLMNA | |
| SCHEMBL8211971 | 0.84 | MAOB (0.53) | L3MBTL1MAOBALDH1A1MAPTLMNA | |
| SCHEMBL6668853 | 0.84 | MAOB (0.53) | L3MBTL1MAOBALDH1A1MAPTLMNA | |
| SCHEMBL23135796 | 0.84 | KDM4E (0.56) | L3MBTL1MAOBALDH1A1MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117486887-A | Polycyclic pyrimidine-4-ketone compound and preparation method and application thereof | 昆明学院 | 2024-02-02 | — | — | CN | disclosed |
| US-5149692-A | Hypotensive agents, congestive heart failure | WARNER-LAMBERT COMPANY (US) | 1992-09-22 | — | — | US | disclosed |