Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC25B | P30305 | 1/20 | 0.43 |
| ▸ | LIG1 | P18858 | 1/20 | 0.37 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | F12 | P00748 | 9/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | GFER | P55789 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19644218 | 0.81 | F12 (0.50) | F12MAPT | |
| SCHEMBL22492714 | 0.81 | F12 (0.45) | ALDH1A1F12 | |
| SCHEMBL19644353 | 0.81 | F12 (0.50) | F12 | |
| SCHEMBL22492362 | 0.79 | F12 (0.47) | F12KDM4EMEN1MAPTKMT2A | |
| SCHEMBL22492639 | 0.78 | F2 (0.48) | ALDH1A1F12KDM4EMEN1GAA | |
| SCHEMBL22492441 | 0.78 | F12 (0.48) | ALDH1A1F12MEN1GAAKMT2A | |
| SCHEMBL9724928 | 0.76 | KDM4E (0.38) | KDM4EMEN1MAPTKMT2A | |
| SCHEMBL9725039 | 0.74 | PTGDR2 (0.32) | — | |
| SCHEMBL768982 | 0.73 | ALDH1A1 (0.54) | ALDH1A1F12 | |
| SCHEMBL30899479 | 0.73 | ALDH1A1 (0.54) | ALDH1A1F12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5112836-A | Autoimmune diseases, antirheumatic agents and metabolic bone diseases | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 1992-05-12 | — | — | US | disclosed |
| CN-1048216-A | Novel ring o-amino benzoyl acid carboxylic acid derivatives | SHU OGIHARA CO LTD (JP) | 1991-01-02 | — | — | CN | disclosed |
| EP-0403980-A1 | Novel cyclic anthranilic acid carboxylic acid derivatives | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 1990-12-27 | — | — | EP | disclosed |