Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.37 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.37 |
| ▸ | AKR1C1 | Q04828 | 2/20 | 0.37 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | PIM1 | P11309 | 3/20 | 0.33 |
| ▸ | PIM2 | Q9P1W9 | 2/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.31 |
| ▸ | AURKA | O14965 | 1/20 | 0.31 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.31 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.31 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.31 |
| ▸ | ABL1 | P00519 | 1/20 | 0.31 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.31 |
| ▸ | RET | P07949 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9724907 | 0.80 | NNMT (0.32) | PIM1CHEK1AURKADAPK3PRKD3 | |
| SCHEMBL9725039 | 0.80 | PTGDR2 (0.32) | PIM1CHEK1AURKADAPK3PRKD3 | |
| SCHEMBL27323304 | 0.76 | — | — | |
| SCHEMBL9724955 | 0.76 | CDC25B (0.43) | KDM4EMEN1MAPTKMT2A | |
| SCHEMBL9724948 | 0.75 | SLC6A2 (0.32) | KDM4EMEN1KMT2A | |
| SCHEMBL9725038 | 0.70 | AKR1C3 (0.36) | KDM4EMEN1MAPTKMT2AAKR1C3 | |
| SCHEMBL9471242 | 0.70 | AKR1C3 (0.42) | KDM4EMEN1MAPTKMT2AAKR1C3 | |
| SCHEMBL9724983 | 0.69 | METAP2 (0.42) | KDM4EMAPT | |
| SCHEMBL9181313 | 0.69 | AKR1C3 (0.38) | KDM4EAKR1C3AKR1C2AKR1C1AKR1C4 | |
| SCHEMBL4035775 | 0.68 | KDM4E (0.43) | KDM4EMEN1MAPTKMT2AAKR1C3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5112836-A | Autoimmune diseases, antirheumatic agents and metabolic bone diseases | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 1992-05-12 | — | — | US | disclosed |
| CN-1048216-A | Novel ring o-amino benzoyl acid carboxylic acid derivatives | SHU OGIHARA CO LTD (JP) | 1991-01-02 | — | — | CN | disclosed |
| EP-0403980-A1 | Novel cyclic anthranilic acid carboxylic acid derivatives | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 1990-12-27 | — | — | EP | disclosed |