Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.60 |
| ▸ | LMNA | P02545 | 4/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 3/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | CA9 | Q16790 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | CNR1 | P21554 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21820774 | 0.85 | ALDH1A1 (0.59) | TSHRLMNAALDH1A1PKMRAB9A | |
| SCHEMBL11753651 | 0.85 | SMN1; SMN2 (0.56) | LMNAALDH1A1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL10944566 | 0.84 | HTT (0.56) | ALDH1A1GAAMEN1KMT2AMAPT | |
| Neburon SCHEMBL8539331 | 0.84 | APEX1 (0.63) | TSHRLMNAALDH1A1GAACA9 | |
| Neburon SCHEMBL27181 | 0.84 | APEX1 (0.63) | TSHRLMNAALDH1A1GAACA9 | |
| SCHEMBL10767909 | 0.83 | TSHR (0.68) | TSHRALDH1A1PKMRAB9AGAA | |
| Neburon SCHEMBL8665655 | 0.83 | PKM (0.61) | TSHRLMNAALDH1A1PTBP1PKM | |
| SCHEMBL21820792 | 0.82 | ALDH1A1 (0.56) | TSHRLMNAALDH1A1PKMRAB9A | |
| SCHEMBL9435552 | 0.80 | GAA (0.56) | TSHRLMNAALDH1A1PTBP1PKM | |
| SCHEMBL7336942 | 0.80 | KMT2A (0.46) | LMNAALDH1A1PTBP1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5099021-A | PROCESS FOR THE PREPARATION OF PURE, UNSYMMETRICALLY DISUBSTITUTED UREAS | AGROLINZ AGRARCHEMIKALIEN GESELLSCHAFT M.B.H. (AT) | 1992-03-24 | — | — | US | disclosed |
| US-4029687-A | HERBICIDES | CIBA-GEIGY AG (CH) | 1977-06-14 | — | — | US | disclosed |
| US-4004914-A | HERBICIDES | CIBA-GEIGY AG (CH) | 1977-01-25 | — | — | US | disclosed |
| US-3951641-A | Use of N-(4-isopropoxy-3-chlorophenyl)-N'-methyl-N'-methoxyurea for control of weeds in maize cultures | CIBA-GEIGY AG (CH) | 1976-04-20 | — | — | US | disclosed |