Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 1/20 | 0.54 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.54 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.54 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.54 |
| ▸ | PLAU | P00749 | 2/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.52 |
| ▸ | SIRT2 | Q8IXJ6 | 2/20 | 0.51 |
| ▸ | TYK2 | P29597 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | PRKDC | P78527 | 1/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | ATR | Q13535 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | PRKCI | P41743 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL392794 | 0.91 | ALDH1A1 (0.59) | HDAC3HDAC1HDAC2NCOR2POLB | |
| Hydrochloric Acid SCHEMBL11743648 | 0.89 | ALDH1A1 (0.58) | HDAC3HDAC1HDAC2NCOR2POLB | |
| SCHEMBL29029890 | 0.86 | ALDH1A1 (0.64) | HDAC3HDAC1HDAC2NCOR2ALDH1A1 | |
| Benzidine SCHEMBL8535004 | 0.81 | FADS1 (0.49) | HDAC3HDAC1HDAC2NCOR2ALDH1A1 | |
| SCHEMBL28997738 | 0.79 | MEN1 (0.53) | HDAC3HDAC1HDAC2NCOR2PLAU | |
| SCHEMBL3071477 | 0.79 | PLAU (0.72) | HDAC3HDAC1HDAC2NCOR2PLAU | |
| SCHEMBL1140055 | 0.79 | PTGS1 (0.68) | HDAC3HDAC1HDAC2NCOR2POLB | |
| Terephthalamide SCHEMBL28143903 | 0.79 | PARP1 (0.46) | POLBALDH1A1KDM4EMAPTHPGD | |
| SCHEMBL18132521 | 0.78 | ALDH1A1 (0.71) | PLAUPOLBRXFP1SIRT2TYK2 | |
| SCHEMBL5668584 | 0.78 | FADS1 (0.62) | SIRT2ALDH1A1MEN1KMT2APTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5124436-A | Solvent soluble | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-06-23 | — | — | US | disclosed |
| US-4987215-A | Filaments, fibers, films, sheets, membranes of very high initial modulus | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-01-22 | — | — | US | disclosed |
| US-4987216-A | Filaments, fibers, films, sheets, membranes of very high initial modulus | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-01-22 | — | — | US | disclosed |