Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 7/20 | 0.68 |
| ▸ | RAB9A | P51151 | 7/20 | 0.68 |
| ▸ | MEN1 | O00255 | 4/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.65 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.65 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.60 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.60 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.60 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.60 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.59 |
| ▸ | GAA | P10253 | 2/20 | 0.58 |
| ▸ | TP53 | P04637 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.58 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.57 |
| ▸ | TERT | O14746 | 1/20 | 0.55 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.55 |
| ▸ | PKM | P14618 | 1/20 | 0.54 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.53 |
| ▸ | GRM5 | P41594 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17675194 | 0.89 | MEN1 (0.71) | NPC1RAB9AMEN1KMT2AKDM4E | |
| SCHEMBL11730893 | 0.86 | MEN1 (0.63) | NPC1RAB9AMEN1KMT2AKDM4E | |
| SCHEMBL2269809 | 0.80 | NPC1 (0.69) | NPC1RAB9AMEN1KMT2AKDM4E | |
| SCHEMBL8433498 | 0.79 | MEN1 (1.00) | NPC1RAB9AMEN1KMT2AKDM4E | |
| SCHEMBL12247953 | 0.78 | NPC1 (0.72) | NPC1RAB9AMEN1KMT2AKDM4E | |
| SCHEMBL2726850 | 0.78 | MEN1 (0.65) | NPC1RAB9AMEN1KMT2AKDM4E | |
| SCHEMBL27771290 | 0.78 | NPC1 (0.64) | NPC1RAB9AKMT2AKDM4EL3MBTL1 | |
| SCHEMBL19747532 | 0.78 | MEN1 (0.69) | NPC1RAB9AMEN1KMT2AKDM4E | |
| SCHEMBL13162953 | 0.78 | MEN1 (0.69) | NPC1RAB9AMEN1KMT2AKDM4E | |
| SCHEMBL14636633 | 0.78 | MEN1 (0.69) | NPC1RAB9AMEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5140020-A | Antiinflammatory agents | KUREHA KAGATU KOGYO KABUSHIKI KAISHA (JP) | 1992-08-18 | — | — | US | disclosed |
| US-4725598-A | Derivative of dihydroxybenzamide and a pharmaceutical composition having an anti-inflammatory activity | KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1988-02-16 | — | — | US | disclosed |
| EP-0142241-B1 | DIHYDROXYBENZAMIDE DERIVATIVES HAVING ANTI-INFLAMMATORY ACTIVITY | KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1987-12-02 | — | — | EP | disclosed |
| EP-0142241-A1 | Dihydroxybenzamide derivatives having anti-inflammatory activity | KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1985-05-22 | — | — | EP | disclosed |