Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.43 |
| ▸ | RAB9A | P51151 | 6/20 | 0.43 |
| ▸ | NPC1 | O15118 | 5/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.41 |
| ▸ | HTT | P42858 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | PPARG | P37231 | 3/20 | 0.41 |
| ▸ | NR2E3 | Q9Y5X4 | 3/20 | 0.41 |
| ▸ | NCOR2 | Q9Y618 | 3/20 | 0.41 |
| ▸ | NCOA2 | Q15596 | 2/20 | 0.41 |
| ▸ | NCOA1 | Q15788 | 2/20 | 0.41 |
| ▸ | NCOA3 | Q9Y6Q9 | 2/20 | 0.41 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 5/20 | 0.40 |
| ▸ | STAT1 | P42224 | 1/20 | 0.38 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.37 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8325747 | 0.73 | RAB9A (0.43) | SMN1; SMN2RAB9ANPC1KDM4EHTT | |
| SCHEMBL15001036 | 0.73 | RAB9A (0.57) | SMN1; SMN2RAB9ANPC1KDM4EHTT | |
| SCHEMBL30076339 | 0.71 | MAPT (0.49) | SMN1; SMN2RAB9ANPC1KDM4EHTT | |
| SCHEMBL28991131 | 0.71 | MAPT (0.49) | SMN1; SMN2RAB9ANPC1KDM4EHTT | |
| SCHEMBL4857995 | 0.71 | APP (0.50) | SMN1; SMN2RAB9ANPC1KDM4EHTT | |
| SCHEMBL9735482 | 0.69 | CDK1 (0.39) | SMN1; SMN2RAB9ANPC1KDM4EALDH1A1 | |
| SCHEMBL17281453 | 0.68 | RAB9A (0.72) | SMN1; SMN2RAB9ANPC1KDM4EHTT | |
| SCHEMBL18133621 | 0.66 | RAB9A (0.70) | SMN1; SMN2RAB9ANPC1KDM4EHTT | |
| SCHEMBL20669009 | 0.66 | RAB9A (0.70) | SMN1; SMN2RAB9ANPC1KDM4EHTT | |
| SCHEMBL15800150 | 0.65 | RAB9A (0.49) | SMN1; SMN2RAB9ANPC1KDM4EHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4018094-A | — | — | None | — | — | JP | disclosed |
| US-5114621-A | INDOLINO-SPIRO-OXAZINE PHOTOCHROMIC COMPOUNDS WITH FIVE-MEMBERED RINGS, METHOD FOR THEIR PREPARATION, PHOTOCHROMIC COMPOSITIONS AND ARTICLES CONTAINING SUCH COMPOUNDS | ESSILOR INTERNATIONAL (COMPAGNIE GENERALE D'OPTIQUE (FR) | 1992-05-19 | — | — | US | disclosed |
| JP-H0418094-A | INDOLINO-SPIRO-OXAZINE PHOTOCHROMIC COMPOUND WITH FIVE-MEMBERED RING, PREPARATION THEREOF, AND PHOTOCHROMIC COMPOSITION AND ARTICLE CONTAINING SUCH COMPOUND | ESSILOR INTERNATL (CIE GEN OPT) | 1992-01-22 | — | — | JP | disclosed |