Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK1 | P06493 | 15/20 | 0.39 |
| ▸ | CDK2 | P24941 | 15/20 | 0.39 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3902435 | 0.72 | CDK1 (0.33) | CDK1CDK2CCNA2L3MBTL1KDM4E | |
| SCHEMBL19737877 | 0.71 | ERN1 (0.47) | CDK1CDK2CCNA2L3MBTL1KDM4E | |
| SCHEMBL2722669 | 0.71 | ALDH1A1 (0.46) | CDK1CDK2CCNA2L3MBTL1KDM4E | |
| SCHEMBL9725178 | 0.69 | SMN1; SMN2 (0.43) | KDM4ENPC1RAB9ATDP1ALDH1A1 | |
| SCHEMBL3173531 | 0.68 | CDK1 (0.33) | CDK1CDK2L3MBTL1KDM4ENPC1 | |
| SCHEMBL5540111 | 0.68 | NPC1 (0.33) | CDK1CDK2CCNA2L3MBTL1KDM4E | |
| SCHEMBL29806829 | 0.67 | ALDH1A1 (0.45) | CDK1CDK2CCNA2L3MBTL1KDM4E | |
| SCHEMBL2093035 | 0.67 | ALDH1A1 (0.45) | CDK1CDK2CCNA2L3MBTL1KDM4E | |
| SCHEMBL27503817 | 0.66 | CDK1 (0.30) | CDK1CDK2CCNA2NPC1RAB9A | |
| SCHEMBL30274237 | 0.66 | GAA (0.38) | KDM4EALDH1A1POLBHPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5114621-A | INDOLINO-SPIRO-OXAZINE PHOTOCHROMIC COMPOUNDS WITH FIVE-MEMBERED RINGS, METHOD FOR THEIR PREPARATION, PHOTOCHROMIC COMPOSITIONS AND ARTICLES CONTAINING SUCH COMPOUNDS | ESSILOR INTERNATIONAL (COMPAGNIE GENERALE D'OPTIQUE (FR) | 1992-05-19 | — | — | US | disclosed |