Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 8/20 | 0.61 |
| ▸ | THRB | P10828 | 8/20 | 0.61 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | SLC5A1 | P13866 | 1/20 | 0.47 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.47 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.44 |
| ▸ | GSR | P00390 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9148552 | 0.87 | THRA (0.59) | THRATHRBL3MBTL1SLC5A1SLC5A2 | |
| SCHEMBL9150875 | 0.87 | THRA (0.59) | THRATHRBLMNAL3MBTL1UTS2R | |
| SCHEMBL9154172 | 0.86 | THRA (0.53) | THRATHRBLMNAKMT2ANPC1 | |
| SCHEMBL9151000 | 0.85 | NPC1 (0.64) | THRATHRBLMNAL3MBTL1MAPT | |
| Hydrochloric Acid SCHEMBL9725207 | 0.85 | THRA (0.58) | THRATHRBLMNAL3MBTL1UTS2R | |
| SCHEMBL4940823 | 0.85 | KMT2A (0.62) | THRATHRBLMNAL3MBTL1MAPT | |
| SCHEMBL9146766 | 0.84 | LMNA (0.67) | THRATHRBLMNA | |
| SCHEMBL9151826 | 0.84 | THRA (0.57) | THRATHRBLMNAL3MBTL1KMT2A | |
| SCHEMBL9152231 | 0.83 | THRA (0.56) | THRATHRBLMNAUTS2R | |
| SCHEMBL9151866 | 0.82 | THRA (0.66) | THRATHRBNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5137920-A | METHOD OF TREATING FUNGAL INFECTIONS | HOFFMANN-LA ROCHE INC. (US) | 1992-08-11 | — | — | US | disclosed |