Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 5/20 | 0.37 |
| ▸ | CA1 | P00915 | 5/20 | 0.37 |
| ▸ | CA2 | P00918 | 5/20 | 0.37 |
| ▸ | CA7 | P43166 | 5/20 | 0.37 |
| ▸ | CA9 | Q16790 | 5/20 | 0.37 |
| ▸ | CA14 | Q9ULX7 | 4/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.32 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.32 |
| ▸ | CA4 | P22748 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | GFER | P55789 | 1/20 | 0.30 |
| ▸ | RXRA | P19793 | 1/20 | 0.30 |
| ▸ | RXRB | P28702 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9725321 | 1.00 | THRB (0.40) | THRBCA12CA1CA2CA7 | |
| SCHEMBL9725286 | 0.87 | CA12 (0.41) | THRBCA12CA1CA2CA7 | |
| SCHEMBL9725285 | 0.87 | CA12 (0.41) | THRBCA12CA1CA2CA7 | |
| SCHEMBL10741689 | 0.83 | THRB (0.55) | THRBCA12CA1CA2CA7 | |
| SCHEMBL24812139 | 0.74 | ALDH1A1 (0.41) | THRBCA12CA1CA2CA7 | |
| SCHEMBL2469181 | 0.70 | TDP1 (0.41) | THRBGAAKDM4E | |
| SCHEMBL4531060 | 0.65 | MAPT (0.39) | ALDH1A1 | |
| SCHEMBL16387187 | 0.65 | CA12 (0.50) | CA12CA1CA2CA7CA9 | |
| SCHEMBL18113230 | 0.65 | CA12 (0.65) | CA12CA1CA2CA7CA9 | |
| SCHEMBL18113144 | 0.65 | CYP2C9 (0.49) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5169838-A | Anticoagulants | FOURNIER INDUSTRIE ET SANTE (FR) | 1992-12-08 | — | — | US | disclosed |