Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP9 | P14780 | 3/20 | 0.68 |
| ▸ | MMP8 | P22894 | 3/20 | 0.68 |
| ▸ | MMP2 | P08253 | 2/20 | 0.68 |
| ▸ | MMP13 | P45452 | 2/20 | 0.68 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.64 |
| ▸ | RAB9A | P51151 | 6/20 | 0.64 |
| ▸ | NPC1 | O15118 | 5/20 | 0.64 |
| ▸ | MAPT | P10636 | 3/20 | 0.64 |
| ▸ | LMNA | P02545 | 2/20 | 0.64 |
| ▸ | GLA | P06280 | 2/20 | 0.64 |
| ▸ | GAA | P10253 | 2/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.61 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.61 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.61 |
| ▸ | RELA | Q04206 | 1/20 | 0.61 |
| ▸ | MGAM | O43451 | 1/20 | 0.60 |
| ▸ | APP | P05067 | 4/20 | 0.59 |
| ▸ | TP53 | P04637 | 1/20 | 0.56 |
| ▸ | MGLL | Q99685 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL505728 | 0.90 | KDM4E (0.69) | MMP9MMP8MMP2MMP13KDM4E | |
| SCHEMBL2702813 | 0.84 | RAB9A (0.64) | MMP9MMP8MMP2MMP13KDM4E | |
| SCHEMBL11339575 | 0.84 | KDM4E (0.64) | MMP9MMP8MMP2MMP13KDM4E | |
| SCHEMBL23169620 | 0.84 | RAB9A (0.64) | MMP9MMP8MMP2MMP13KDM4E | |
| SCHEMBL29474819 | 0.83 | RAB9A (0.81) | MMP9MMP8MMP2MMP13KDM4E | |
| SCHEMBL366824 | 0.83 | RAB9A (0.81) | MMP9MMP8MMP2MMP13KDM4E | |
| SCHEMBL31472989 | 0.82 | MMP2 (0.69) | MMP9MMP8MMP2MMP13KDM4E | |
| SCHEMBL28608538 | 0.82 | MMP2 (0.69) | MMP9MMP8MMP2MMP13KDM4E | |
| SCHEMBL1987139 | 0.81 | MMP2 (1.00) | MMP9MMP8MMP2MMP13KDM4E | |
| SCHEMBL754574 | 0.81 | RAB9A (0.73) | MMP9MMP8MMP2MMP13KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5081256-A | Para ordered aromatic diacids containing benzimidazole groups | UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE (US) | 1992-01-14 | — | — | US | disclosed |
| US-4892953-A | Benzthiazole substituted diacid terphenyl monomers | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE (US) | 1990-01-09 | — | — | US | disclosed |