Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDPK1 | O15530 | 1/20 | 0.61 |
| ▸ | NPC1 | O15118 | 8/20 | 0.58 |
| ▸ | RAB9A | P51151 | 7/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.58 |
| ▸ | PKM | P14618 | 2/20 | 0.58 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.58 |
| ▸ | TP53 | P04637 | 1/20 | 0.58 |
| ▸ | AMY1A | P0DUB6 | 2/20 | 0.55 |
| ▸ | HPGD | P15428 | 4/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | HTT | P42858 | 2/20 | 0.54 |
| ▸ | GAA | P10253 | 2/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.54 |
| ▸ | GLA | P06280 | 1/20 | 0.54 |
| ▸ | ESR1 | P03372 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16050074 | 0.93 | PDPK1 (0.54) | PDPK1NPC1RAB9AALDH1A1KDM4E | |
| SCHEMBL16050067 | 0.88 | AMY1A (0.57) | PDPK1NPC1RAB9AALDH1A1KDM4E | |
| SCHEMBL16050128 | 0.88 | AMY1A (0.53) | PDPK1NPC1RAB9AALDH1A1KDM4E | |
| SCHEMBL31429607 | 0.87 | AMY1A (0.62) | PDPK1NPC1RAB9AALDH1A1KDM4E | |
| SCHEMBL16050075 | 0.86 | AMY1A (0.52) | PDPK1NPC1RAB9AALDH1A1KDM4E | |
| SCHEMBL15396523 | 0.86 | ALDH1A1 (0.67) | PDPK1NPC1RAB9AALDH1A1KDM4E | |
| SCHEMBL2898110 | 0.86 | NPC1 (0.67) | PDPK1NPC1RAB9AALDH1A1KDM4E | |
| SCHEMBL1283869 | 0.86 | NPC1 (0.67) | PDPK1NPC1RAB9AALDH1A1KDM4E | |
| SCHEMBL31429747 | 0.86 | F2 (0.62) | PDPK1NPC1RAB9AALDH1A1KDM4E | |
| SCHEMBL3512712 | 0.86 | NPC1 (0.67) | PDPK1NPC1RAB9AALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5081256-A | Para ordered aromatic diacids containing benzimidazole groups | UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE (US) | 1992-01-14 | — | — | US | disclosed |
| US-5081256-A | Para ordered aromatic diacids containing benzimidazole groups | UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE (US) | 1992-01-14 | — | — | US | disclosed |