SCHEMBL9725339

SCHEMBL9725339

CCN(CCOc1ccc(C=C(C#N)C(=O)OC)cc1)c1ccc(C=C(C#N)C(=O)OC)cc1

nearest known ligand 0.56

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 8/20 0.55
ALDH1A1 P00352 8/20 0.55
MEN1 O00255 7/20 0.55
MAPT P10636 6/20 0.55
POLB P06746 2/20 0.55
L3MBTL1 Q9Y468 4/20 0.49
TDP1 Q9NUW8 4/20 0.49
MAPK1 P28482 3/20 0.49
LMNA P02545 2/20 0.49
NPSR1 Q6W5P4 2/20 0.49
USP2 O75604 1/20 0.49
RECQL P46063 1/20 0.49
BLM P54132 1/20 0.49
KDM4E B2RXH2 3/20 0.48
PSMD14 O00487 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9725336 1.00 KMT2A (0.55) KMT2AALDH1A1MEN1MAPTPOLB
SCHEMBL15371881 0.90 ALDH1A1 (0.55) KMT2AALDH1A1MEN1MAPTPOLB
SCHEMBL15371885 0.87 ALDH1A1 (0.52) KMT2AALDH1A1MEN1MAPTPOLB
SCHEMBL21457222 0.87 MEN1 (0.71) KMT2AALDH1A1MEN1MAPTPOLB
SCHEMBL1779264 0.87 MEN1 (0.71) KMT2AALDH1A1MEN1MAPTPOLB
SCHEMBL1779263 0.87 MEN1 (0.71) KMT2AALDH1A1MEN1MAPTPOLB
SCHEMBL15371860 0.85 ALDH1A1 (0.43) KMT2AALDH1A1MEN1MAPTPOLB
SCHEMBL10694789 0.84 KDM4E (0.59) KMT2AALDH1A1MEN1MAPTL3MBTL1
SCHEMBL10694794 0.84 KDM4E (0.59) KMT2AALDH1A1MEN1MAPTL3MBTL1
SCHEMBL12477636 0.83 ALDH1A1 (0.56) KMT2AALDH1A1MEN1MAPTL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5086161-A Ultraviolet radiation screening food packaging EASTMAN KODAK COMPANY (US) 1992-02-04 US disclosed
US-5075491-A Ultraviolet radiation absorbers EASTMAN KODAK COMPANY (US) 1991-12-24 US disclosed
US-5068348-A For food packaging EASTMAN KODAK COMPANY (US) 1991-11-26 US disclosed
US-4958043-A Novel methine compounds, polymers containing them and formed articles therefrom EASTMAN KODAK COMPANY (US) 1990-09-18 US disclosed