SCHEMBL1779264

SCHEMBL1779264

CCN(CC)c1ccc(C=C(C#N)C(=O)OC)cc1

nearest known ligand 0.72

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 6/20 0.71
KMT2A Q03164 6/20 0.71
ALDH1A1 P00352 6/20 0.71
MAPT P10636 5/20 0.71
POLB P06746 2/20 0.71
MAPK1 P28482 3/20 0.63
L3MBTL1 Q9Y468 3/20 0.63
TDP1 Q9NUW8 2/20 0.63
NPSR1 Q6W5P4 2/20 0.63
LMNA P02545 2/20 0.62
USP2 O75604 1/20 0.62
RECQL P46063 1/20 0.62
BLM P54132 1/20 0.62
PSMD14 O00487 1/20 0.51
APP P05067 1/20 0.50
KDM4E B2RXH2 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21457222 1.00 MEN1 (0.71) MEN1KMT2AALDH1A1MAPTPOLB
SCHEMBL1779263 1.00 MEN1 (0.71) MEN1KMT2AALDH1A1MAPTPOLB
SCHEMBL14701171 0.88 ALDH1A1 (0.69) MEN1KMT2AALDH1A1MAPTPOLB
SCHEMBL21457457 0.88 ALDH1A1 (0.69) MEN1KMT2AALDH1A1MAPTPOLB
SCHEMBL14701316 0.88 ALDH1A1 (0.69) MEN1KMT2AALDH1A1MAPTPOLB
SCHEMBL1781014 0.87 SLC16A3 (0.55) MEN1KMT2AALDH1A1MAPTPOLB
SCHEMBL1781017 0.87 SLC16A3 (0.55) MEN1KMT2AALDH1A1MAPTPOLB
SCHEMBL9725336 0.87 KMT2A (0.55) MEN1KMT2AALDH1A1MAPTPOLB
SCHEMBL9725339 0.87 KMT2A (0.55) MEN1KMT2AALDH1A1MAPTPOLB
SCHEMBL14703499 0.86 MEN1 (0.67) MEN1KMT2AALDH1A1MAPTPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7517695-B2 Local flow and shear stress sensor based on molecular rotors THE CURATORS OF THE UNIVERSITY OF MISSOURI (US) 2009-04-14 US claimed
EP-3553097-B1 COPOLYMER AND OPTICAL FILM USING SAME TOSOH CORP (JP) 2022-05-04 EP disclosed
US-11225540-B2 Copolymer and optical film using same TOSOH CORPORATION (JP) 2022-01-18 US disclosed
CN-110248971-B Copolymer and optical film using the same 东曹株式会社 2021-11-02 CN disclosed
US-20200095358-A1 COPOLYMER AND OPTICAL FILM USING SAME TOSOH CORPORATION (JP) 2020-03-26 US disclosed
EP-3553097-A1 COPOLYMER AND OPTICAL FILM USING SAME Tosoh Corporation (JP) 2019-10-16 EP disclosed
US-20160185753-A1 DEUTERATED DIAMINOPYRIMIDINE COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS COMPRISING SUCH COMPOUNDS SUZHOU ZELGEN BIOPHARMACEUTICALS CO., LTD. (CN) 2016-06-30 US disclosed
US-7943390-B2 Supported molecular biofluid viscosity sensors for in vitro and in vivo use THE CURATORS OF THE UNIVERSITY OF MISSOURI (US) 2011-05-17 US disclosed
US-7670844-B2 Supported molecular biofluid viscosity sensors for in vitro and in vivo use THE CURATORS OF THE UNIVERSITY OF MISSOURI (US) 2010-03-02 US disclosed
US-20090227880-A1 SUPPORTED MOLECULAR BIOFLUID VISCOSITY SENSORS FOR IN VITRO AND IN VIVO USE THE CURATORS OF THE UNIVERSITY OF MISSOURI (US) 2009-09-10 US disclosed
US-7517695-B2 Local flow and shear stress sensor based on molecular rotors THE CURATORS OF THE UNIVERSITY OF MISSOURI (US) 2009-04-14 US disclosed
US-20060084177-A1 Supported molecular biofluid viscosity sensors for in vitro and in vivo use THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2006-04-20 US disclosed
US-20060079001-A1 Local flow and shear stress sensor based on molecular rotors THE CURATORS OF THE UNIVERSITY OF MISSOURI 2006-04-13 US disclosed
WO-2005073697-A1 LOCAL FLOW AND SHEAR STRESS SENSOR BASED ON MOLECULAR ROTORS THE CURATORS OF THE UNIVERSITY OF MISSOURI (US) 2005-08-11 WO disclosed
WO-2005072216-A2 SUPPORTED MOLECULAR BIOFLUID VISCOSITY SENSORS FOR IN VITRO AND IN VIVO USE THE CURATORS OF THE UNIVERSITY OF MISSOURI (US) 2005-08-11 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160185753-A1 DEUTERATED DIAMINOPYRIMIDINE COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS COMPRISING SUCH COMPOUNDS DCK, DPYD, PDCD1 MEN1 1496/4885KMT2A 1386/4885ALDH1A1 2610/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.