Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 1/20 | 0.51 |
| ▸ | PGR | P06401 | 4/20 | 0.50 |
| ▸ | MPO | P05164 | 4/20 | 0.49 |
| ▸ | XDH | P47989 | 3/20 | 0.49 |
| ▸ | CBX7 | O95931 | 1/20 | 0.47 |
| ▸ | CDYL2 | Q8N8U2 | 1/20 | 0.47 |
| ▸ | CDYL | Q9Y232 | 1/20 | 0.47 |
| ▸ | CDY1; CDY1B | Q9Y6F8 | 1/20 | 0.47 |
| ▸ | CCR4 | P51679 | 1/20 | 0.46 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9725385 | 0.99 | MPO (0.50) | DAOPGRMPOXDHCBX7 | |
| SCHEMBL9725403 | 0.84 | DAO (0.53) | DAOPGRMPOCCR4MEN1 | |
| Hydrochloric Acid SCHEMBL9725357 | 0.83 | DAO (0.51) | DAOPGRMPOCCR4MEN1 | |
| SCHEMBL9725430 | 0.83 | MPO (0.45) | PGRMPOCCR4MEN1KMT2A | |
| SCHEMBL9725422 | 0.83 | DAO (0.51) | DAOPGRMPOXDHCCR4 | |
| SCHEMBL11708301 | 0.82 | DAO (0.57) | DAOPGRCBX7CDYL2CDYL | |
| Hydrochloric Acid SCHEMBL9725529 | 0.82 | MPO (0.44) | PGRMPOCCR4MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL9725500 | 0.82 | MPO (0.50) | DAOPGRMPOXDHCCR4 | |
| SCHEMBL10284498 | 0.81 | PGR (0.64) | DAOPGRCBX7CDYL2CDYL | |
| SCHEMBL318631 | 0.81 | DAO (0.55) | DAOPGRCBX7CDYL2CDYL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0454330-A1 | Benzimidazolinone derivatives | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1991-10-30 | — | — | EP | claimed |
| US-5162318-A | Which have pulmonary surfactant secretion promoting activity | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1992-11-10 | — | — | US | disclosed |
| EP-0454330-A1 | Benzimidazolinone derivatives | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1991-10-30 | — | — | EP | disclosed |