Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.55 |
| ▸ | GAA | P10253 | 8/20 | 0.55 |
| ▸ | HPGD | P15428 | 5/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.55 |
| ▸ | GLA | P06280 | 4/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.55 |
| ▸ | HTT | P42858 | 2/20 | 0.55 |
| ▸ | PKM | P14618 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | RAD52 | P43351 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | CCR4 | P51679 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | PPARG | P37231 | 1/20 | 0.44 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.44 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9725495 | 0.99 | ALDH1A1 (0.54) | ALDH1A1KDM4EGAAHPGDKMT2A | |
| SCHEMBL5320024 | 0.86 | ALDH1A1 (0.58) | ALDH1A1KDM4EGAAHPGDKMT2A | |
| SCHEMBL9725434 | 0.85 | ALDH1A1 (0.43) | ALDH1A1KDM4EGAAHPGDKMT2A | |
| Hydrochloric Acid SCHEMBL9725433 | 0.84 | ALDH1A1 (0.43) | ALDH1A1KDM4EGAAHPGDKMT2A | |
| SCHEMBL14530088 | 0.82 | ALDH1A1 (0.54) | ALDH1A1KDM4EGAAHPGDKMT2A | |
| SCHEMBL4915808 | 0.81 | KDM4E (0.53) | ALDH1A1KDM4EGAAHPGDKMT2A | |
| SCHEMBL9725445 | 0.80 | KDM4E (0.49) | ALDH1A1KDM4EHPGDHSD17B10CCR4 | |
| SCHEMBL15687345 | 0.79 | SMN1; SMN2 (0.58) | ALDH1A1KDM4EGAAHPGDKMT2A | |
| SCHEMBL4254017 | 0.79 | KDM4E (0.54) | ALDH1A1KDM4EGAAHPGDKMT2A | |
| Hydrochloric Acid SCHEMBL9725523 | 0.79 | KDM4E (0.48) | ALDH1A1KDM4EHPGDHSD17B10RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5162318-A | Which have pulmonary surfactant secretion promoting activity | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1992-11-10 | — | — | US | disclosed |
| EP-0454330-A1 | Benzimidazolinone derivatives | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1991-10-30 | — | — | EP | disclosed |