Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | CCR4 | P51679 | 1/20 | 0.47 |
| ▸ | HTR2A | P28223 | 2/20 | 0.46 |
| ▸ | HTR2C | P28335 | 2/20 | 0.46 |
| ▸ | HTR6 | P50406 | 4/20 | 0.44 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.44 |
| ▸ | CALCRL | Q16602 | 1/20 | 0.43 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.43 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.43 |
| ▸ | PDE2A | O00408 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | HTR1D | P28221 | 1/20 | 0.41 |
| ▸ | HTR1E | P28566 | 1/20 | 0.41 |
| ▸ | HTR7 | P34969 | 1/20 | 0.41 |
| ▸ | HTR5A | P47898 | 1/20 | 0.41 |
| ▸ | MYLK | Q15746 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9725523 | 0.99 | KDM4E (0.48) | KDM4EALDH1A1HPGDHSD17B10CCR4 | |
| SCHEMBL9725490 | 0.89 | HTR2A (0.49) | KDM4EALDH1A1HPGDHSD17B10CCR4 | |
| Hydrochloric Acid SCHEMBL9725431 | 0.88 | HTR2A (0.48) | KDM4EALDH1A1HPGDHSD17B10CCR4 | |
| SCHEMBL9725370 | 0.82 | DAO (0.53) | ALDH1A1HPGDCCR4CALCRLPDE3B | |
| Hydrochloric Acid SCHEMBL9725468 | 0.81 | DAO (0.51) | ALDH1A1HPGDCCR4CALCRLPDE3B | |
| SCHEMBL9725470 | 0.81 | MPO (0.45) | ALDH1A1HPGDCCR4LMNAMPO | |
| SCHEMBL9725479 | 0.81 | CCR4 (0.56) | KDM4EALDH1A1HPGDHSD17B10CCR4 | |
| SCHEMBL8125879 | 0.80 | KMO (0.55) | KDM4EALDH1A1HPGDHSD17B10DYRK1A | |
| SCHEMBL9725397 | 0.80 | ALDH1A1 (0.55) | KDM4EALDH1A1HPGDHSD17B10CCR4 | |
| Hydrochloric Acid SCHEMBL9725461 | 0.80 | CCR4 (0.55) | KDM4EALDH1A1HSD17B10CCR4HTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5162318-A | Which have pulmonary surfactant secretion promoting activity | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1992-11-10 | — | — | US | disclosed |
| EP-0454330-A1 | Benzimidazolinone derivatives | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1991-10-30 | — | — | EP | disclosed |