Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.72 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.72 |
| ▸ | LMNA | P02545 | 1/20 | 0.72 |
| ▸ | MAPT | P10636 | 1/20 | 0.72 |
| ▸ | HSD17B3 | P37058 | 7/20 | 0.68 |
| ▸ | CES2 | O00748 | 2/20 | 0.66 |
| ▸ | CES1 | P23141 | 2/20 | 0.66 |
| ▸ | HTR7 | P34969 | 1/20 | 0.66 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.64 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.64 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.64 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.64 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.64 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.64 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.64 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.64 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.64 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.64 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.64 |
| ▸ | NPC1 | O15118 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Valerophenone SCHEMBL50014 | 1.00 | L3MBTL1 (0.72) | L3MBTL1TDP1LMNAMAPTHSD17B3 | |
| Valerophenone SCHEMBL5615151 | 1.00 | L3MBTL1 (0.72) | L3MBTL1TDP1LMNAMAPTHSD17B3 | |
| Valerophenone SCHEMBL27921461 | 0.98 | L3MBTL1 (0.69) | L3MBTL1TDP1LMNAMAPTHSD17B3 | |
| Valerophenone SCHEMBL9858470 | 0.98 | L3MBTL1 (0.69) | L3MBTL1TDP1LMNAMAPTHSD17B3 | |
| SCHEMBL9725525 | 0.94 | L3MBTL1 (0.76) | L3MBTL1TDP1LMNAMAPTHSD17B3 | |
| SCHEMBL50000 | 0.94 | L3MBTL1 (0.76) | L3MBTL1TDP1LMNAMAPTHSD17B3 | |
| SCHEMBL962630 | 0.92 | L3MBTL1 (0.80) | L3MBTL1TDP1LMNAMAPTHSD17B3 | |
| SCHEMBL967963 | 0.92 | L3MBTL1 (0.80) | L3MBTL1TDP1LMNAMAPTHSD17B3 | |
| SCHEMBL964590 | 0.92 | L3MBTL1 (0.80) | L3MBTL1TDP1LMNAMAPTHSD17B3 | |
| SCHEMBL22528986 | 0.92 | L3MBTL1 (0.80) | L3MBTL1TDP1LMNAMAPTHSD17B3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5162318-A | Which have pulmonary surfactant secretion promoting activity | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1992-11-10 | — | — | US | disclosed |
| EP-0279681-A2 | Saturated heterocyclic carboxamide derivatives | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1988-08-24 | — | — | EP | disclosed |