Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.72 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.72 |
| ▸ | LMNA | P02545 | 1/20 | 0.72 |
| ▸ | MAPT | P10636 | 1/20 | 0.72 |
| ▸ | HSD17B3 | P37058 | 7/20 | 0.68 |
| ▸ | CES2 | O00748 | 2/20 | 0.66 |
| ▸ | CES1 | P23141 | 2/20 | 0.66 |
| ▸ | HTR7 | P34969 | 1/20 | 0.66 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.64 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.64 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.64 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.64 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.64 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.64 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.64 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.64 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.64 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.64 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.64 |
| ▸ | NPC1 | O15118 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Valerophenone SCHEMBL50014 | 1.00 | L3MBTL1 (0.72) | L3MBTL1TDP1LMNAMAPTHSD17B3 | |
| Valerophenone SCHEMBL9725402 | 1.00 | L3MBTL1 (0.72) | L3MBTL1TDP1LMNAMAPTHSD17B3 | |
| Valerophenone SCHEMBL27921461 | 0.98 | L3MBTL1 (0.69) | L3MBTL1TDP1LMNAMAPTHSD17B3 | |
| Valerophenone SCHEMBL9858470 | 0.98 | L3MBTL1 (0.69) | L3MBTL1TDP1LMNAMAPTHSD17B3 | |
| SCHEMBL9725525 | 0.94 | L3MBTL1 (0.76) | L3MBTL1TDP1LMNAMAPTHSD17B3 | |
| SCHEMBL50000 | 0.94 | L3MBTL1 (0.76) | L3MBTL1TDP1LMNAMAPTHSD17B3 | |
| SCHEMBL962630 | 0.92 | L3MBTL1 (0.80) | L3MBTL1TDP1LMNAMAPTHSD17B3 | |
| SCHEMBL967963 | 0.92 | L3MBTL1 (0.80) | L3MBTL1TDP1LMNAMAPTHSD17B3 | |
| SCHEMBL964590 | 0.92 | L3MBTL1 (0.80) | L3MBTL1TDP1LMNAMAPTHSD17B3 | |
| SCHEMBL22528986 | 0.92 | L3MBTL1 (0.80) | L3MBTL1TDP1LMNAMAPTHSD17B3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8722681-B2 | N-sulfonyl thiazolylpiperazine derivatives and related N-sulfonyl heterocyclic derivatives for the treatment of neuro degenerative diseases | NV REMYND (BE) | 2014-05-13 | — | — | US | disclosed |
| US-7288677-B2 | Diimines and secondary diamines | ALBEMARLE CORPORATION (US) | 2007-10-30 | — | — | US | disclosed |
| US-20060217567-A1 | Diimines and secondary diamines | ALBEMARLE CORPORATION | 2006-09-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060217567-A1 | Diimines and secondary diamines | DDT, DDC, AOC1 | L3MBTL1 2969/4885TDP1 1225/4885LMNA 3166/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.