Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 7/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28927450 | 0.86 | TRPA1 (0.42) | TRPA1POLB | |
| SCHEMBL19439529 | 0.82 | CAPN1 (0.42) | TRPA1LMNAMEN1KMT2ATAAR1 | |
| SCHEMBL13452609 | 0.82 | LMNA (0.46) | TRPA1LMNAMEN1KMT2ATAAR1 | |
| SCHEMBL3276260 | 0.82 | LMNA (0.46) | TRPA1LMNAMEN1KMT2ATAAR1 | |
| SCHEMBL218804 | 0.82 | LMNA (0.46) | TRPA1LMNAMEN1KMT2ATAAR1 | |
| SCHEMBL10627463 | 0.82 | CYP2D6 (0.42) | LMNAKMT2ATAAR1CYP2D6 | |
| SCHEMBL5085704 | 0.76 | HRH1 (0.48) | TRPA1LMNAFFAR1MEN1KMT2A | |
| SCHEMBL3685590 | 0.75 | AOC3 (0.42) | LMNAKMT2APOLBCYP2D6 | |
| SCHEMBL21308579 | 0.75 | AOC3 (0.42) | LMNAKMT2APOLBCYP2D6 | |
| SCHEMBL5468931 | 0.74 | KMT2A (0.40) | LMNAMEN1KMT2ACYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5162318-A | Which have pulmonary surfactant secretion promoting activity | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1992-11-10 | — | — | US | disclosed |
| EP-0454330-A1 | Benzimidazolinone derivatives | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1991-10-30 | — | — | EP | disclosed |