Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | MAOB | P27338 | 1/20 | 0.49 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.44 |
| ▸ | HTR1A | P08908 | 1/20 | 0.44 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.44 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.44 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.44 |
| ▸ | DRD1 | P21728 | 1/20 | 0.44 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.44 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.44 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.44 |
| ▸ | DRD3 | P35462 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | BRD4 | O60885 | 1/20 | 0.42 |
| ▸ | DDR1 | Q08345 | 9/20 | 0.41 |
| ▸ | CTSK | P43235 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9725560 | 0.99 | KDM4E (0.51) | KDM4EALDH1A1MAOBABCB11HTR1A | |
| SCHEMBL9725486 | 0.90 | MAPT (0.48) | KDM4EALDH1A1MAOBABCB11HTR1A | |
| Hydrochloric Acid SCHEMBL9725510 | 0.88 | MAPT (0.47) | KDM4EALDH1A1MAOBABCB11HTR1A | |
| SCHEMBL9725422 | 0.82 | DAO (0.51) | MAOBCCR4PGR | |
| SCHEMBL4953055 | 0.82 | KDM4E (0.52) | KDM4EALDH1A1MAOBABCB11HTR1A | |
| Hydrochloric Acid SCHEMBL9725500 | 0.81 | MPO (0.50) | MAOBCCR4PGR | |
| SCHEMBL9725403 | 0.81 | DAO (0.53) | BRD4CCR4PGR | |
| SCHEMBL9725430 | 0.80 | MPO (0.45) | SLC6A4OPRM1CCR4PGR | |
| Hydrochloric Acid SCHEMBL9725357 | 0.80 | DAO (0.51) | BRD4CCR4PGR | |
| SCHEMBL9725376 | 0.80 | DAO (0.51) | ALDH1A1MAOBCCR4PGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5162318-A | Which have pulmonary surfactant secretion promoting activity | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1992-11-10 | — | — | US | disclosed |
| EP-0454330-A1 | Benzimidazolinone derivatives | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1991-10-30 | — | — | EP | disclosed |