Methacrylic Acid

Methacrylic Acid

SCHEMBL9725557

C=C(C)C(=O)O.C=CC(=O)O.C[SiH](C)O[SiH3]

nearest known ligand 0.42

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Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.42
ALOX15 P16050 1/20 0.38
HSD17B10 Q99714 1/20 0.38
ALDH1A1 P00352 3/20 0.35
TP53 P04637 1/20 0.31
TSHR P16473 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Methacrylic Acid SCHEMBL3360715 0.89 ALDH1A1 (0.36) HSD17B10ALDH1A1
Methacrylic Acid SCHEMBL440900 0.89 ALDH1A1 (0.36) HSD17B10ALDH1A1
Acrylic Acid SCHEMBL2526676 0.89 LMNA (0.53) LMNAALOX15HSD17B10ALDH1A1TSHR
Acrylic Acid SCHEMBL8018695 0.85 ALDH1A1 (0.54) LMNAALOX15HSD17B10ALDH1A1TSHR
Acrylic Acid SCHEMBL5613188 0.83 LMNA (0.46) LMNAALOX15HSD17B10ALDH1A1TSHR
Methacrylic Acid SCHEMBL9467142 0.82 LMNA (0.56) LMNAALOX15HSD17B10ALDH1A1TP53
Methacrylic Acid SCHEMBL23071293 0.82 LMNA (0.62) LMNAALOX15HSD17B10ALDH1A1TP53
Methacrylic Acid SCHEMBL9681348 0.82 LMNA (0.62) LMNAALOX15HSD17B10ALDH1A1TP53
Methacrylic Acid SCHEMBL137716 0.82 LMNA (0.62) LMNAALOX15HSD17B10ALDH1A1TP53
Methacrylic Acid SCHEMBL9066064 0.82 LMNA (0.62) LMNAALOX15HSD17B10ALDH1A1TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5086141-A Polysiloxane crosslinked styrene/butadiene copolymers XEROX CORPORATION (US) 1992-02-04 US disclosed
US-4954408-A Polysiloxane crosslinked styrene/butadiene copolymers XEROX CORPORATION (US) 1990-09-04 US disclosed