SCHEMBL9725656

SCHEMBL9725656

CCCCNC(=O)SCC

nearest known ligand 0.50

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
EPHX1 P07099 6/20 0.50
ACHE P22303 8/20 0.47
MMP2 P08253 2/20 0.47
HTT P42858 2/20 0.42
TSHR P16473 1/20 0.42
MMP1 P03956 1/20 0.42
CASP2 P42575 1/20 0.42
MEN1 O00255 1/20 0.41
KMT2A Q03164 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10784886 0.93 EPHX1 (0.56) EPHX1CASP2
SCHEMBL27334816 0.91 EPHX1 (0.59) EPHX1CASP2
SCHEMBL11810464 0.86 EPHX1 (0.50) EPHX1ACHEMMP2HTTTSHR
S-Ethyl Propylcarbamothioate SCHEMBL10974251 0.86
SCHEMBL15512673 0.84 ALDH1A1 (0.49) EPHX1ACHEMMP2HTTTSHR
SCHEMBL6692189 0.81 EPHX1 (0.55) EPHX1ACHECASP2
SCHEMBL15548955 0.81 PLA2G4A (0.47) TSHRMEN1KMT2A
SCHEMBL14602831 0.81 EPHX1 (0.55) EPHX1ACHECASP2
SCHEMBL11847159 0.81 EPHX1 (0.55) EPHX1ACHECASP2
SCHEMBL9678864 0.79 EPHX1 (0.44) EPHX1ACHEMMP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5171356-A Thiolcarbamate and nonphytotoxic extender which minimizes soil degradation ICI AMERICAS INC. (US) 1992-12-15 US disclosed
EP-0175332-B1 HERBICIDE COMPOSITIONS OF EXTENDED SOIL LIFE STAUFFER CHEMICAL COMPANY (US) 1992-03-18 EP disclosed
US-4762548-A HALOALLYL-SUBSTITUTED AMIDE EXTENDER FOR A THIOLCARBAMATE STAUFFER CHEMICAL CO. (US) 1988-08-09 US disclosed
US-4695314-A S-benzyl thiolcarbamates and their use in controlling weeds in rice fields STAUFFER CHEMICAL COMPANY (US) 1987-09-22 US disclosed
US-4613358-A THIOLCARBAMATE HERBICIDES, ORGANOPHOSPHORUS EXTENDERS STAUFFER CHEMICAL CO. (US) 1986-09-23 US disclosed
EP-0083648-B1 S-BENZYL THIOLCARBAMATES AND THEIR USE IN CONTROLLING WEEDS IN RICE FIELDS STAUFFER CHEMICAL COMPANY (US) 1986-06-04 EP disclosed
EP-0175332-A2 Herbicide compositions of extended soil life STAUFFER CHEMICAL COMPANY (US) 1986-03-26 EP disclosed
US-4545805-A A THIOCARBAMATE AND 1,4-DIOXANEMETHYLDIETHYL THIONOPHOSPHATE STAUFFER CHEMICAL COMPANY (US) 1985-10-08 US disclosed
US-4433999-A THIOCARBAMATES, CARBAMATE AND AN ANTIDOTE STAUFFER CHEMICAL COMPANY (US) 1984-02-28 US disclosed
EP-0083648-A4 S-BENZYL THIOLCARBAMATES AND THEIR USE IN CONTROLLING WEEDS IN RICE FIELDS. STAUFFER CHEMICAL CO (US) 1984-01-10 EP disclosed
EP-0083648-A1 S-BENZYL THIOLCARBAMATES AND THEIR USE IN CONTROLLING WEEDS IN RICE FIELDS. STAUFFER CHEMICAL CO (US) 1983-07-20 EP disclosed
US-4381936-A CARBAMATE STABILIZER WITH A THIOCARBAMATE STAUFFER CHEMICAL COMPANY (US) 1983-05-03 US disclosed
US-4380468-A RETARDS AND STABILIZES THIOLCARBAMATES AGAINST SOIL BIODEGRADATION STAUFFER CHEMICAL COMPANY (US) 1983-04-19 US disclosed
WO-1983000329-A1 S-BENZYL THIOLCARBAMATES AND THEIR USE IN CONTROLLING WEEDS IN RICE FIELDS STAUFFER CHEMICAL CO (US) 1983-02-03 WO disclosed
EP-0038945-A2 Herbicide compositions of extended soil life STAUFFER CHEMICAL COMPANY (US) 1981-11-04 EP disclosed