Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | MITF | O75030 | 1/20 | 0.42 |
| ▸ | CASP6 | P55212 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | BCHE | P06276 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | BACE1 | P56817 | 1/20 | 0.40 |
| ▸ | SLC11A2 | P49281 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.37 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27414020 | 0.91 | MAPT (0.42) | MAPTKDM4EKMT2APOLBLMNA | |
| SCHEMBL8798919 | 0.87 | MAPT (0.38) | MAPTKDM4EKMT2APOLBLMNA | |
| SCHEMBL8798925 | 0.87 | MAPT (0.38) | MAPTKDM4EKMT2APOLBLMNA | |
| SCHEMBL8798560 | 0.86 | KMT2A (0.39) | MAPTKDM4EKMT2APOLBLMNA | |
| SCHEMBL27372688 | 0.84 | CYP1A2 (0.44) | MAPTKDM4EKMT2APOLBLMNA | |
| SCHEMBL27373748 | 0.84 | CYP1A2 (0.44) | MAPTKDM4EKMT2APOLBLMNA | |
| SCHEMBL8799087 | 0.83 | MAPT (0.36) | MAPTKDM4EKMT2APOLBLMNA | |
| SCHEMBL27315485 | 0.83 | GPR119 (0.41) | KMT2APOLBMEN1ALDH1A1CYP1A2 | |
| SCHEMBL27315479 | 0.83 | ALDH1A1 (0.42) | MAPTKDM4EKMT2APOLBLMNA | |
| SCHEMBL655542 | 0.82 | MEN1 (0.40) | KMT2APOLBMEN1ALDH1A1BACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4178375-A | — | — | None | — | — | JP | disclosed |
| CN-1182838-C | Intraorally soluble compressed molding and process for producing the same | ֮����ҩ��ʽ���� | 2005-01-05 | — | — | CN | disclosed |
| CN-1139878-A | Intraorally soluble compressed molding and process for producing the same | YAMANOUCHI PHARMA CO LTD (JP) | 1997-01-08 | — | — | CN | disclosed |
| CN-1029479-C | Process for preparing benzoxazine derivatives | YAMANOUCHI PHARMACEUTICAL KK (JP) | 1995-08-09 | — | — | CN | disclosed |
| CN-1100422-A | Novel derivative of benoxazine and pharmaceutical composition containing same | YAMANOUCHI PHARMA CO LTD (JP) | 1995-03-22 | — | — | CN | disclosed |
| CN-1100423-A | Novel derivative of benoxazine and pharmaceutical composition containing same | YAMANOUCHI PHARMA CO LTD (JP) | 1995-03-22 | — | — | CN | disclosed |
| JP-H04178375-A | NEW BENZOXAZINE DERIVATIVE, INTERMEDIATE AND DRUG THEREOF | YAMANOUCHI PHARMACEUT CO LTD | 1992-06-25 | — | — | JP | disclosed |