Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | REN | P00797 | 5/20 | 0.47 |
| ▸ | CTSL | P07711 | 2/20 | 0.46 |
| ▸ | CTSB | P07858 | 1/20 | 0.46 |
| ▸ | CTSS | P25774 | 1/20 | 0.46 |
| ▸ | CTSK | P43235 | 1/20 | 0.46 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.42 |
| ▸ | PTPRB | P23467 | 1/20 | 0.42 |
| ▸ | BACE1 | P56817 | 3/20 | 0.42 |
| ▸ | CTSD | P07339 | 1/20 | 0.42 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.42 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.41 |
| ▸ | PSEN1 | P49768 | 2/20 | 0.41 |
| ▸ | PSEN2 | P49810 | 2/20 | 0.41 |
| ▸ | APH1B | Q8WW43 | 2/20 | 0.41 |
| ▸ | NCSTN | Q92542 | 2/20 | 0.41 |
| ▸ | APH1A | Q96BI3 | 2/20 | 0.41 |
| ▸ | PSENEN | Q9NZ42 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9849789 | 1.00 | GAA (0.47) | GAAL3MBTL1RENCTSLCTSB | |
| SCHEMBL7295320 | 0.91 | CA1 (0.44) | RENCTSLCTSBCTSSCTSK | |
| SCHEMBL7295314 | 0.91 | CA1 (0.44) | RENCTSLCTSBCTSSCTSK | |
| SCHEMBL9725752 | 0.91 | CA1 (0.44) | RENCTSLCTSBCTSSCTSK | |
| SCHEMBL9725745 | 0.91 | CA1 (0.44) | RENCTSLCTSBCTSSCTSK | |
| SCHEMBL7309940 | 0.91 | CA1 (0.44) | RENCTSLCTSBCTSSCTSK | |
| SCHEMBL9741250 | 0.90 | BACE1 (0.45) | GAAL3MBTL1RENCTSLCTSB | |
| SCHEMBL9741242 | 0.90 | BACE1 (0.45) | GAAL3MBTL1RENCTSLCTSB | |
| SCHEMBL9741069 | 0.87 | REN (0.47) | GAAL3MBTL1RENCTSSCTSK | |
| SCHEMBL9741074 | 0.87 | REN (0.47) | GAAL3MBTL1RENCTSSCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0427939-A2 | Renin inhibitors | AMERICAN CYANAMID COMPANY (US) | 1991-05-22 | — | — | EP | disclosed |