SCHEMBL9725762

SCHEMBL9725762

CC(C)OCCc1ccc(O)cc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 4/20 0.52
ESR2 Q92731 2/20 0.52
CA2 P00918 1/20 0.46
CALM1 P0DP23 1/20 0.46
TAAR1 Q96RJ0 4/20 0.45
SLC6A2 P23975 4/20 0.45
TMEM97 Q5BJF2 1/20 0.45
SIGMAR1 Q99720 1/20 0.45
ALDH1A1 P00352 3/20 0.45
ADRA2A P08913 3/20 0.45
KDM4E B2RXH2 2/20 0.45
HTR1A P08908 1/20 0.45
CYP2C19 P33261 1/20 0.45
HTR3A P46098 1/20 0.45
BACE1 P56817 1/20 0.45
L3MBTL1 Q9Y468 1/20 0.45
ADORA3 P0DMS8 2/20 0.44
TACR2 P21452 2/20 0.44
SLC6A4 P31645 2/20 0.44
SLC6A3 Q01959 2/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL274512 0.84 ESR1 (0.48) ESR1ESR2CA2CALM1TAAR1
SCHEMBL10448894 0.82 ESR1 (0.46) ESR1ESR2CA2CALM1TAAR1
SCHEMBL14499021 0.81 CYP1A2 (0.46) TAAR1ALDH1A1CYP3A4MAPTRAB9A
SCHEMBL21100525 0.81 CALM1 (0.38) ESR1ESR2CA2CALM1TAAR1
SCHEMBL11979782 0.80 TAAR1 (0.50) ESR1ESR2CA2CALM1TAAR1
SCHEMBL3369539 0.80 ADRB2 (0.54) ESR1ESR2CA2TAAR1SLC6A2
SCHEMBL9253919 0.80 ESR1 (0.46) ESR1ESR2CA2CALM1TAAR1
SCHEMBL19120785 0.79 KMT2A (0.50) TAAR1SLC6A2KDM4EL3MBTL1SLC6A4
Methyl Alcohol SCHEMBL28147273 0.79 TSHR (0.44) CA2ALDH1A1TDP1
SCHEMBL20419199 0.79 ADRB2 (0.40) ALDH1A1L3MBTL1LMNAADRB3HIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5124489-A Process for preparing phenethanol ethers by the reduction of corresponding phenylglyoxal acetals HOECHST CELANESE CORPORATION (US) 1992-06-23 US disclosed