Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 12/20 | 0.47 |
| ▸ | CTSB | P07858 | 9/20 | 0.47 |
| ▸ | PTPRB | P23467 | 1/20 | 0.46 |
| ▸ | REN | P00797 | 1/20 | 0.46 |
| ▸ | CTSS | P25774 | 3/20 | 0.45 |
| ▸ | CTSK | P43235 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9725802 | 0.90 | REN (0.49) | REN | |
| SCHEMBL7269394 | 0.90 | REN (0.49) | REN | |
| SCHEMBL7268135 | 0.90 | REN (0.49) | REN | |
| SCHEMBL7284863 | 0.86 | REN (0.51) | CTSLCTSBPTPRBRENCTSS | |
| SCHEMBL7284859 | 0.86 | REN (0.51) | CTSLCTSBPTPRBRENCTSS | |
| SCHEMBL9725883 | 0.82 | REN (0.48) | CTSLCTSBRENCTSSCTSK | |
| SCHEMBL9725771 | 0.82 | REN (0.47) | CTSLCTSBRENCTSSCTSK | |
| SCHEMBL9725737 | 0.81 | REN (0.50) | CTSLCTSBPTPRBRENCTSS | |
| SCHEMBL9725773 | 0.81 | REN (0.46) | CTSLCTSBRENCTSSCTSK | |
| SCHEMBL7269368 | 0.80 | REN (0.51) | CTSLCTSBRENCTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5106835-A | Hypotensive agents | AMERICAN CYANAMID COMPANY (US) | 1992-04-21 | — | — | US | disclosed |