Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 6/20 | 0.51 |
| ▸ | CAPN1 | P07384 | 2/20 | 0.47 |
| ▸ | CTSL | P07711 | 2/20 | 0.47 |
| ▸ | CTSB | P07858 | 2/20 | 0.47 |
| ▸ | MME | P08473 | 1/20 | 0.47 |
| ▸ | ANPEP | P15144 | 1/20 | 0.47 |
| ▸ | CTSS | P25774 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7269371 | 1.00 | REN (0.51) | RENCAPN1CTSLCTSBMME | |
| SCHEMBL9725737 | 0.87 | REN (0.50) | RENCAPN1CTSLCTSBCTSS | |
| SCHEMBL7275371 | 0.86 | REN (0.50) | RENCAPN1CTSLCTSB | |
| SCHEMBL7284859 | 0.86 | REN (0.51) | RENCAPN1CTSLCTSBCTSS | |
| SCHEMBL7284863 | 0.86 | REN (0.51) | RENCAPN1CTSLCTSBCTSS | |
| SCHEMBL7278858 | 0.85 | REN (0.57) | REN | |
| SCHEMBL7267680 | 0.83 | REN (0.45) | REN | |
| SCHEMBL9725771 | 0.81 | REN (0.47) | RENCAPN1CTSLCTSBCTSS | |
| SCHEMBL9725765 | 0.80 | CTSL (0.47) | RENCTSLCTSBCTSS | |
| SCHEMBL7269828 | 0.80 | REN (0.61) | RENCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0376040-A2 | N-phosphinyl di-and tripeptides as renin inhibitors | AMERICAN CYANAMID COMPANY (US) | 1990-07-04 | — | — | EP | disclosed |