Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC1A3 | P43003 | 2/20 | 0.46 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.46 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.46 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.46 |
| ▸ | MAOA | P21397 | 1/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.46 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.46 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.46 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.46 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.41 |
| ▸ | TACR1 | P25103 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9725844 | 1.00 | SLC1A3 (0.46) | SLC1A3SLC1A2SLC1A1CYP2D6MEN1 | |
| SCHEMBL11599252 | 1.00 | SLC1A3 (0.46) | SLC1A3SLC1A2SLC1A1CYP2D6MEN1 | |
| SCHEMBL22995900 | 0.80 | CYP2D6 (0.50) | SLC1A3SLC1A2SLC1A1CYP2D6MEN1 | |
| SCHEMBL22628599 | 0.80 | CYP2D6 (0.50) | SLC1A3SLC1A2SLC1A1CYP2D6MEN1 | |
| SCHEMBL8204507 | 0.80 | CYP2D6 (0.50) | SLC1A3SLC1A2SLC1A1CYP2D6MEN1 | |
| SCHEMBL6141169 | 0.78 | SLC1A3 (0.43) | SLC1A3SLC1A2SLC1A1CYP2D6MEN1 | |
| SCHEMBL6239307 | 0.78 | SLC1A3 (0.43) | SLC1A3SLC1A2SLC1A1CYP2D6MEN1 | |
| SCHEMBL562232 | 0.76 | SLC1A1 (0.68) | SLC1A3SLC1A2SLC1A1CYP2D6MEN1 | |
| SCHEMBL288385 | 0.76 | SLC1A1 (0.68) | SLC1A3SLC1A2SLC1A1CYP2D6MEN1 | |
| SCHEMBL8464720 | 0.76 | SLC1A1 (0.68) | SLC1A3SLC1A2SLC1A1CYP2D6MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4146614-A | TREATMENT OF SCHIZOPHRENIA | STATE OF MICHIGAN (US) | 1979-03-27 | — | — | US | claimed |
| US-5100875-A | NOVEL PEPTIDES HAVING PLATELER AGGREGATION INHIBITORY ACTIVITY | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) | 1992-03-31 | — | — | US | disclosed |