Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC1A1 | P43005 | 10/20 | 0.68 |
| ▸ | SLC1A2 | P43004 | 9/20 | 0.68 |
| ▸ | SLC1A3 | P43003 | 8/20 | 0.68 |
| ▸ | MEN1 | O00255 | 1/20 | 0.68 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.68 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.68 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.68 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.68 |
| ▸ | SLC15A1 | P46059 | 1/20 | 0.49 |
| ▸ | MMP9 | P14780 | 2/20 | 0.47 |
| ▸ | MMP8 | P22894 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | ALPI | P09923 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.46 |
| ▸ | XIAP | P98170 | 1/20 | 0.46 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.46 |
| ▸ | LTA4H | P09960 | 1/20 | 0.44 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31606672 | 1.00 | SLC1A1 (0.68) | SLC1A1SLC1A2SLC1A3MEN1CYP1A2 | |
| SCHEMBL18325959 | 1.00 | SLC1A1 (0.68) | SLC1A1SLC1A2SLC1A3MEN1CYP1A2 | |
| SCHEMBL14037383 | 1.00 | SLC1A1 (0.68) | SLC1A1SLC1A2SLC1A3MEN1CYP1A2 | |
| SCHEMBL289127 | 1.00 | SLC1A1 (0.68) | SLC1A1SLC1A2SLC1A3MEN1CYP1A2 | |
| SCHEMBL8464720 | 1.00 | SLC1A1 (0.68) | SLC1A1SLC1A2SLC1A3MEN1CYP1A2 | |
| SCHEMBL288386 | 1.00 | SLC1A1 (0.68) | SLC1A1SLC1A2SLC1A3MEN1CYP1A2 | |
| SCHEMBL562232 | 1.00 | SLC1A1 (0.68) | SLC1A1SLC1A2SLC1A3MEN1CYP1A2 | |
| Hydrochloric Acid SCHEMBL20820005 | 0.98 | SLC1A1 (0.66) | SLC1A1SLC1A2SLC1A3MEN1CYP1A2 | |
| Hydrochloric Acid SCHEMBL15670199 | 0.98 | SLC1A1 (0.66) | SLC1A1SLC1A2SLC1A3MEN1CYP1A2 | |
| Hydrochloric Acid SCHEMBL3334189 | 0.98 | SLC1A1 (0.66) | SLC1A1SLC1A2SLC1A3MEN1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9695191-B2 | Conformationally constrained, fully synthetic macrocyclic compounds | POLYPHOR AG (CH) | 2017-07-04 | — | — | US | claimed |
| EP-2462147-B1 | CONFORMATIONALLY CONSTRAINED, FULLY SYNTHETIC MACROCYCLIC COMPOUNDS | POLYPHOR AG (CH) | 2014-11-12 | — | — | EP | claimed |
| US-20120202821-A1 | CONFORMATIONALLY CONSTRAINED, FULLY SYNTHETIC MACROCYCLIC COMPOUNDS | POLYPHOR AG (CH) | 2012-08-09 | — | — | US | claimed |
| CN-115515937-A | Dimers for the synthesis of peptidomimetics | 范因斯坦医学研究院 | 2022-12-23 | — | — | CN | disclosed |
| EP-3087094-B1 | BETA-HAIRPIN PEPTIDOMIMETICS AS SELECTIVE ELASTASE INHIBITORS | POLYPHOR AG (CH) | 2022-06-01 | — | — | EP | disclosed |
| US-10273267-B2 | Beta-hairpin peptidomimetics as selective elastase inhibitors | POLYPHOR AG (CH) | 2019-04-30 | — | — | US | disclosed |
| US-20170369523-A1 | TEMPLATE-FIXED BETA-HAIRPIN PEPTIDOMIMETICS THAT ARE LIGANDS FOR G-PROTEIN-COUPLED RECEPTORS (GPCRS) AND ARE MODULATORS OF TRANSCRIPTION FACTORS AND COACTIVATORS | POLYPHOR AG (CH) | 2017-12-28 | — | — | US | disclosed |
| US-9695191-B2 | Conformationally constrained, fully synthetic macrocyclic compounds | POLYPHOR AG (CH) | 2017-07-04 | — | — | US | disclosed |
| US-20160333053-A1 | BETA-HAIRPIN PEPTIDOMIMETICS AS SELECTIVE ELASTASE INHIBITORS | POLYPHOR AG (CH) | 2016-11-17 | — | — | US | disclosed |
| EP-3087094-A1 | BETA-HAIRPIN PEPTIDOMIMETICS AS SELECTIVE ELASTASE INHIBITORS | Polyphor AG (CH) | 2016-11-02 | — | — | EP | disclosed |
| US-9284352-B2 | Beta-hairpin peptidomimetics having CXCR4 antagonizing activity | POLYPHOR AG (CH) | 2016-03-15 | — | — | US | disclosed |
| US-5859052-A | TREATING LENTIVIRUS INFECTIONS, ESPECIALLY HUMAN IMMUNODEFICIENCY VIRUS | G. D. SEARLE & CO. (US) | 1999-01-12 | — | — | US | disclosed |
| US-5744631-A | Fatty acid analogs and prodrugs | G.D. SEARLE & CO. (US) | 1998-04-28 | — | — | US | disclosed |
| US-5719290-A | METHYLOXYUNDECYL- OR DECYLOXYETHYL-NITRILE OR TETRAZOLE DERIVATIVES; VIRICIDES | G. D. SEARLE & CO. (US) | 1998-02-17 | — | — | US | disclosed |
| US-5672769-A | CHEMICAL INTERMEDIATES FOR VIRICIDES, FUNGICIDES | G. D. SEARLE & CO. (US) | 1997-09-30 | — | — | US | disclosed |
| US-5670650-A | ANTIVIRAL AND ANTIFUNGAL AGENTS | G. D. SEARLE & CO. (US) | 1997-09-23 | — | — | US | disclosed |
| US-5599947-A | VIRICIDES, FUNGICIDES OR THEIR PRODRUGS | G. D. SEARLE & CO. (US) | 1997-02-04 | — | — | US | disclosed |
| US-4745124-A | THIO/ESTER PEPTIDES | UNIVERSITY OF MIAMI (US) | 1988-05-17 | — | — | US | disclosed |
| US-4690936-A | AMINO ACIDS, THIOESTER LINKAGE; ANGIOTENSIN INHIBITORS | UNIVERSITY OF MIAMI (US) | 1987-09-01 | — | — | US | disclosed |
| US-4127521-A | ANALGESIC | VETERANS ADMINISTRATION, THE UNITED STATES OF AMERICA AS REPRESENTED BY | 1978-11-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120202821-A1 | CONFORMATIONALLY CONSTRAINED, FULLY SYNTHETIC MACROCYCLIC COMPOUNDS | HTR2B, MC1R, HTR1A | SLC1A1 2314/4885SLC1A2 1491/4885SLC1A3 2430/4885 |
| US-20160333053-A1 | BETA-HAIRPIN PEPTIDOMIMETICS AS SELECTIVE ELASTASE INHIBITORS | SERPINB1, ELANE, XPNPEP1 | SLC1A1 2889/4885SLC1A2 3434/4885SLC1A3 2520/4885 |
| US-10273267-B2 | Beta-hairpin peptidomimetics as selective elastase inhibitors | SERPINB1, ELANE, XPNPEP1 | SLC1A1 2889/4885SLC1A2 3434/4885SLC1A3 2520/4885 |
| US-20170369523-A1 | TEMPLATE-FIXED BETA-HAIRPIN PEPTIDOMIMETICS THAT ARE LIGANDS FOR G-PROTEIN-COUPLED RECEPTORS (GPCRS) AND ARE MODULATORS OF TRANSCRIPTION FACTORS AND COACTIVATORS | NCOA1, NCOA2, NCOR1 | SLC1A1 3823/4885SLC1A2 3782/4885SLC1A3 3910/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.