Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 3/20 | 0.49 |
| ▸ | NTSR1 | P30989 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | MMP9 | P14780 | 1/20 | 0.44 |
| ▸ | MMP8 | P22894 | 1/20 | 0.44 |
| ▸ | MMP14 | P50281 | 1/20 | 0.44 |
| ▸ | LTA4H | P09960 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1087101 | 0.77 | KMT2A (0.49) | MMEMMP9 | |
| SCHEMBL1086444 | 0.77 | KMT2A (0.49) | MMEMMP9 | |
| SCHEMBL5840489 | 0.75 | MMP2 (0.49) | MMP9 | |
| SCHEMBL6152839 | 0.75 | MMP2 (0.49) | MMP9 | |
| SCHEMBL17530042 | 0.74 | MMP9 (0.55) | MMEMMP9MMP8MMP14 | |
| SCHEMBL17530041 | 0.74 | MMP9 (0.55) | MMEMMP9MMP8MMP14 | |
| SCHEMBL18722285 | 0.74 | MMP9 (0.55) | MMEMMP9MMP8MMP14 | |
| SCHEMBL8862571 | 0.74 | MME (0.52) | MMELTA4H | |
| SCHEMBL8862574 | 0.74 | MME (0.52) | MMELTA4H | |
| SCHEMBL8248672 | 0.73 | FOLH1 (0.55) | MMEMMP9MMP8MMP14LTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5098892-A | Angiotensin converting enzyme inhibitors as hypotensive agents | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1992-03-24 | — | — | US | disclosed |