SCHEMBL9726175

SCHEMBL9726175

C[C@H](NC(=O)[C@@H](Cc1c[nH]c2ccccc12)NC(=O)[C@@H](N)Cc1c[nH]cn1)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@H](Cc1ccccc1)C(=O)N[C@@H](CCCCN)C(N)=O

nearest known ligand 0.66

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
GHSR Q92847 15/20 0.66

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30675098 1.00 GHSR (0.66) GHSR
SCHEMBL28021776 1.00 GHSR (0.66) GHSR
SCHEMBL9726172 1.00 GHSR (0.66) GHSR
SCHEMBL29973265 0.95 GHSR (0.60) GHSR
Examorelin SCHEMBL28022186 0.94 GHSR (0.60) GHSR
Examorelin SCHEMBL29403103 0.94 GHSR (0.60) GHSR
Examorelin SCHEMBL29805730 0.94 GHSR (0.60) GHSR
Examorelin SCHEMBL26959 0.94 GHSR (0.60) GHSR
Examorelin SCHEMBL6219689 0.93 GHSR (0.59) GHSR
Examorelin SCHEMBL8580589 0.93 GHSR (0.59) GHSR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11628133-B2 Uses of the peptide of sequence His-D-Trp-Ala-Trp-d-Phe-Lys-NH2 for reducing or delaying the appearance of cell senescence and signs of skin aging ISP INVESTMENTS LLC (US) 2023-04-18 US claimed
US-20250360156-A1 SYNERGISTIC COMBINATION OF NAD+ AND THERAPEUTIC PEPTIDES DELIVERED VIA IONTOPHORESIS FOR ENHANCED AND PROLONGED REGENERATIVE EFFECTS ANDREWS NICHOLAS JEROME (US) 2025-11-27 US disclosed
US-20240158438-A1 POLYPEPTIDE COMPOUND AND APPLICATION THEREOF CHENGDU SINTANOVO BIOTECHNOLOGY CO., LTD. (CN) 2024-05-16 US disclosed
EP-4321525-A1 POLYPEPTIDE COMPOUND AND APPLICATION THEREOF Chengdu Sintanovo Biotechnology Co., Ltd (CN) 2024-02-14 EP disclosed
US-20230330187-A1 USE OF GHRELIN OR GHRELIN VARIANT FOR INCREASING DOSE INTENSITY OF CHEMOTHERAPEUTIC AGENTS IN PATIENTS WITH CANCER OXEIA BIOPHARMACEUTICALS INC (US) 2023-10-19 US disclosed
US-11628133-B2 Uses of the peptide of sequence His-D-Trp-Ala-Trp-d-Phe-Lys-NH2 for reducing or delaying the appearance of cell senescence and signs of skin aging ISP INVESTMENTS LLC (US) 2023-04-18 US disclosed
US-11628133-B2 Uses of the peptide of sequence His-D-Trp-Ala-Trp-d-Phe-Lys-NH2 for reducing or delaying the appearance of cell senescence and signs of skin aging ISP INVESTMENTS LLC (US) 2023-04-18 US disclosed
EP-2981292-B1 SUPRAMOLECULAR AGGREGATES COMPRISING A MALEIMIDO CORE UFPEPTIDES S R L (IT) 2022-11-02 EP disclosed
WO-2022226116-A1 GHRELIN TREATMENT OF BRAIN DYSFUNCTION DUE TO VIRAL INFECTION OXEIA BIOPHARMACEUTICALS, INC. (US) 2022-10-27 WO disclosed
WO-2022206587-A1 POLYPEPTIDE COMPOUND AND APPLICATION THEREOF 成都诺和晟泰生物科技有限公司 2022-10-06 WO disclosed
EP-3182992-A1 METHODS OF TREATING MILD BRAIN INJURY Oxeia Biopharmaceuticals Inc. (US) 2017-06-28 EP disclosed
US-20170121385-A1 METHODS OF TREATING NEURODEGENERATIVE CONDITIONS OXEIA BIOPHARMACEUTICALS, INC. (US) 2017-05-04 US disclosed
WO-2017075535-A1 METHODS OF TREATING NEURODEGENERATIVE CONDITIONS OXEIA BIOPHARMACEUTICALS, INC. (US) 2017-05-04 WO disclosed
WO-2016048488-A1 METHODS OF TREATING TRAUMATIC BRAIN INJURY OXEIA BIOPHARMACEUTICALS, INC. (US) 2016-03-31 WO disclosed
WO-2016028826-A1 METHODS OF TREATING MILD BRAIN INJURY OXEIA BIOPHARMACEUTICALS, INC. (US) 2016-02-25 WO disclosed
US-20150265680-A1 THERAPEUTIC AGENT FOR AMYOTROPHIC LATERAL SCLEROSIS DAIICHI SANKYO COMPANY, LIMITED (JP) 2015-09-24 US disclosed
EP-2913063-A1 THERAPEUTIC AGENT FOR AMYOTROPHIC LATERAL SCLEROSIS DAIICHI SANKYO COMPANY, LIMITED (JP) 2015-09-02 EP disclosed
US-5137874-A For parenteral administration AMERICAN CYANAMID CO. (US) 1992-08-11 US disclosed
EP-0211267-B1 CONTINUOUS RELEASE PEPTIDE COMPOSITIONS AMERICAN CYANAMID COMPANY (US) 1990-12-05 EP disclosed
EP-0211267-A2 Continuous release peptide compositions AMERICAN CYANAMID COMPANY (US) 1987-02-25 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240158438-A1 POLYPEPTIDE COMPOUND AND APPLICATION THEREOF GHSR, GHRHR, GIPR GHSR 1/4885
US-20170121385-A1 METHODS OF TREATING NEURODEGENERATIVE CONDITIONS HTT, SNCA, NLN GHSR 64/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.