Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | EPHX1 | P07099 | 10/20 | 0.39 |
| ▸ | ADH1B | P00325 | 2/20 | 0.39 |
| ▸ | ADH1C | P00326 | 2/20 | 0.39 |
| ▸ | ADH1A | P07327 | 2/20 | 0.39 |
| ▸ | ADH7 | P40394 | 2/20 | 0.39 |
| ▸ | ADH4 | P08319 | 1/20 | 0.39 |
| ▸ | PPARA | Q07869 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | CASP2 | P42575 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9726226 | 1.00 | ALDH1A1 (0.42) | ALDH1A1TSHREPHX1ADH1BADH1C | |
| SCHEMBL4543673 | 1.00 | ALDH1A1 (0.42) | ALDH1A1TSHREPHX1ADH1BADH1C | |
| SCHEMBL7348833 | 0.98 | EPHX1 (0.43) | ALDH1A1TSHREPHX1ADH1BADH1C | |
| SCHEMBL7674469 | 0.93 | — | — | |
| SCHEMBL8030867 | 0.93 | — | — | |
| SCHEMBL4716785 | 0.82 | — | — | |
| SCHEMBL5194477 | 0.82 | — | — | |
| SCHEMBL1257120 | 0.81 | ALDH1A1 (0.42) | ALDH1A1TSHREPHX1ADH1BADH1C | |
| SCHEMBL7338190 | 0.80 | ALDH1A1 (0.37) | ALDH1A1TSHREPHX1ADH1BADH1C | |
| SCHEMBL8707061 | 0.79 | ALDH1A1 (0.40) | ALDH1A1TSHREPHX1ADH1BADH1C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5116817-A | LHRH preparations for intranasal administration | SYNTEX (U.S.A.) INC. (US) | 1992-05-26 | — | — | US | claimed |
| EP-0111841-B1 | LHRH PREPARATIONS FOR INTRANASAL ADMINISTRATION | SYNTEX (U.S.A.) INC. (US) | 1987-05-06 | — | — | EP | claimed |
| US-4476116-A | HORMONES; PROTEINS; ENZYMERS | SYNTEX (U.S.A.) INC. (US) | 1984-10-09 | — | — | US | claimed |
| EP-0111841-A1 | LHRH preparations for intranasal administration | SYNTEX (U.S.A.) INC. (US) | 1984-06-27 | — | — | EP | claimed |
| US-5116817-A | LHRH preparations for intranasal administration | SYNTEX (U.S.A.) INC. (US) | 1992-05-26 | — | — | US | disclosed |
| EP-0111841-B1 | LHRH PREPARATIONS FOR INTRANASAL ADMINISTRATION | SYNTEX (U.S.A.) INC. (US) | 1987-05-06 | — | — | EP | disclosed |
| US-4476116-A | HORMONES; PROTEINS; ENZYMERS | SYNTEX (U.S.A.) INC. (US) | 1984-10-09 | — | — | US | disclosed |
| EP-0111841-A1 | LHRH preparations for intranasal administration | SYNTEX (U.S.A.) INC. (US) | 1984-06-27 | — | — | EP | disclosed |