⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4716785 | 1.00 | — | — | |
| SCHEMBL7674469 | 0.84 | — | — | |
| SCHEMBL8030867 | 0.84 | — | — | |
| SCHEMBL4543673 | 0.82 | ALDH1A1 (0.42) | — | |
| SCHEMBL9726224 | 0.82 | ALDH1A1 (0.42) | — | |
| SCHEMBL9726226 | 0.82 | ALDH1A1 (0.42) | — | |
| SCHEMBL7348833 | 0.80 | EPHX1 (0.43) | — | |
| SCHEMBL3027384 | 0.80 | — | — | |
| SCHEMBL1047066 | 0.80 | — | — | |
| SCHEMBL11191939 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1811982-A1 | THERAPEUTIC TREATMENT OF ACCELERATED BONE RESORPTION | Can-Fite Biopharma Ltd. (IL) | 2007-08-01 | — | — | EP | claimed |
| WO-2006048884-A1 | THERAPEUTIC TREATMENT OF ACCELERATED BONE RESORPTION | CAN-FITE BIOPHARMA LTD. (IL) | 2006-05-11 | — | — | WO | claimed |
| EP-3681538-A1 | A3 ADENOSINE RECEPTOR LIGAND FOR MANAGING CYTOKINE RELEASE SYNDROME | Can-Fite Biopharma Ltd. (IL) | 2020-07-22 | — | — | EP | disclosed |
| WO-2019053723-A1 | A3 ADENOSINE RECEPTOR LIGAND FOR MANAGING CYTOKINE RELEASE SYNDROME | CAN-FITE BIOPHARMA LTD (IL) | 2019-03-21 | — | — | WO | disclosed |