Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 3/20 | 0.34 |
| ▸ | HTR2A | P28223 | 2/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
| ▸ | HTR7 | P34969 | 1/20 | 0.34 |
| ▸ | HTR6 | P50406 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.34 |
| ▸ | DRD1 | P21728 | 2/20 | 0.32 |
| ▸ | DRD3 | P35462 | 2/20 | 0.32 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.32 |
| ▸ | CES1 | P23141 | 2/20 | 0.31 |
| ▸ | HTR2C | P28335 | 1/20 | 0.31 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11045883 | 0.70 | ALDH1A1 (0.62) | DRD2MEN1KMT2AALDH1A1DRD3 | |
| SCHEMBL9726221 | 0.69 | HTR2A (0.64) | DRD2HTR2AHTR1AHTR7HTR6 | |
| SCHEMBL5638347 | 0.65 | ALDH1A1 (0.64) | DRD2MEN1KMT2AALDH1A1DRD3 | |
| SCHEMBL9726206 | 0.65 | HTR2A (0.62) | DRD2HTR2AHTR1AHTR7HTR6 | |
| SCHEMBL24327019 | 0.64 | ALDH1A1 (0.33) | ALDH1A1MAPTMAPK1SMN1; SMN2 | |
| SCHEMBL31256046 | 0.62 | HTR2A (0.66) | DRD2HTR2AHTR1AHTR7HTR6 | |
| SCHEMBL7793840 | 0.61 | HTR2A (0.59) | DRD2HTR2AHTR1AHTR7HTR6 | |
| SCHEMBL11183187 | 0.61 | ALDH1A1 (0.68) | DRD2MEN1KMT2AALDH1A1DRD3 | |
| SCHEMBL1763849 | 0.61 | MEN1 (0.58) | DRD2MEN1KMT2ADRD3GRIN2B | |
| SCHEMBL19122704 | 0.61 | CES1 (0.53) | MEN1KMT2AALDH1A1CES1HTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5130313-A | Central nervous system disorders, cardiovascular disorders or gastrointestinal disorders | RHONE-POULENC SANTE (FR) | 1992-07-14 | — | — | US | disclosed |