Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.61 |
| ▸ | HTR1A | P08908 | 1/20 | 0.57 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6162058 | 0.84 | SIGMAR1 (0.60) | SIGMAR1HTR1AKCNA3 | |
| SCHEMBL5541146 | 0.84 | SIGMAR1 (0.60) | SIGMAR1HTR1AKCNA3 | |
| SCHEMBL14601668 | 0.84 | SIGMAR1 (0.60) | SIGMAR1HTR1AKCNA3 | |
| SCHEMBL9867159 | 0.84 | SIGMAR1 (0.60) | SIGMAR1HTR1AKCNA3 | |
| SCHEMBL9726237 | 0.84 | SIGMAR1 (0.60) | SIGMAR1HTR1AKCNA3 | |
| SCHEMBL10231292 | 0.83 | SIGMAR1 (0.68) | SIGMAR1HTR1A | |
| Bromide SCHEMBL9869119 | 0.83 | SIGMAR1 (0.59) | SIGMAR1HTR1AKCNA3 | |
| Hydrochloric Acid SCHEMBL9868303 | 0.83 | SIGMAR1 (0.59) | SIGMAR1HTR1AKCNA3 | |
| SCHEMBL7297566 | 0.83 | SIGMAR1 (0.63) | SIGMAR1HTR1AKCNA3 | |
| SCHEMBL5544346 | 0.83 | SIGMAR1 (0.63) | SIGMAR1HTR1AKCNA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5130313-A | Central nervous system disorders, cardiovascular disorders or gastrointestinal disorders | RHONE-POULENC SANTE (FR) | 1992-07-14 | — | — | US | disclosed |
| US-4999355-A | Antiserotonine agents | RHONE-POULENC (FR) | 1991-03-12 | — | — | US | disclosed |