Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 12/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | BLM | P54132 | 1/20 | 0.55 |
| ▸ | AGER | Q15109 | 1/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | NAPRT | Q6XQN6 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
| ▸ | ASPH | Q12797 | 3/20 | 0.39 |
| ▸ | KDM8 | Q8N371 | 3/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Quinolinic Acid SCHEMBL27449062 | 0.82 | KDM4E (0.76) | KDM4EALDH1A1ALOX15MAPTCYP3A4 | |
| Carbromal SCHEMBL518268 | 0.78 | KDM4E (0.40) | KDM4EALDH1A1ALOX15TSHRBLM | |
| Carbromal SCHEMBL8536554 | 0.78 | CRBN (0.36) | — | |
| Carbromal SCHEMBL5972678 | 0.77 | ALDH1A1 (0.45) | ALDH1A1ALOX15MAPTCYP3A4TSHR | |
| Carbromal SCHEMBL8656167 | 0.76 | KDM4E (0.39) | KDM4EALDH1A1ALOX15TSHRBLM | |
| Quinolinic Acid SCHEMBL14687247 | 0.76 | KDM4E (0.81) | KDM4EALDH1A1ALOX15MAPTCYP3A4 | |
| Carbromal SCHEMBL7904148 | 0.76 | TRPV1 (0.43) | KDM4EALDH1A1CYP1A2 | |
| Quinolinic Acid SCHEMBL27725715 | 0.76 | KDM4E (0.88) | KDM4EALDH1A1ALOX15MAPTCYP3A4 | |
| Quinolinic Acid SCHEMBL27862037 | 0.76 | KDM4E (0.88) | KDM4EALDH1A1ALOX15MAPTCYP3A4 | |
| Carbromal SCHEMBL6249616 | 0.76 | CRBN (0.37) | MAPTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5142055-A | Dehydrofluorinating reduced fluoroalkyl pyridine compound | MONSANTO COMPANY (US) | 1992-08-25 | — | — | US | disclosed |
| US-4978384-A | HERBICIDES | MONSANTO COMPANY (US) | 1990-12-18 | — | — | US | disclosed |
| US-4826530-A | PREEEMERGENCE AND SELECTIVE POSTEMEREGENCE HERBICIDES | MONSANTO COMPANY (US) | 1989-05-02 | — | — | US | disclosed |