Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BPTF | Q12830 | 2/20 | 0.50 |
| ▸ | BRD4 | O60885 | 4/20 | 0.46 |
| ▸ | BRD9 | Q9H8M2 | 3/20 | 0.46 |
| ▸ | KAT2B | Q92831 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.41 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | PDE9A | O76083 | 2/20 | 0.40 |
| ▸ | F2 | P00734 | 1/20 | 0.39 |
| ▸ | F10 | P00742 | 1/20 | 0.39 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.39 |
| ▸ | F7 | P08709 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10599611 | 0.95 | BPTF (0.47) | BPTFBRD4BRD9KAT2BMAPT | |
| SCHEMBL9726609 | 0.87 | BPTF (0.46) | BPTFBRD4BRD9KAT2BPOLB | |
| SCHEMBL9726598 | 0.87 | BPTF (0.52) | BPTFBRD4BRD9KAT2BMAPT | |
| SCHEMBL10601786 | 0.86 | BPTF (0.53) | BPTFBRD4BRD9KAT2BTP53 | |
| SCHEMBL9726487 | 0.85 | BRD4 (0.50) | BPTFBRD4BRD9KAT2BMAPT | |
| SCHEMBL9726528 | 0.84 | BRD4 (0.52) | BPTFBRD4BRD9KAT2BMAPT | |
| SCHEMBL9726869 | 0.84 | BPTF (0.49) | BPTFBRD4BRD9KAT2BPOLB | |
| SCHEMBL9726397 | 0.83 | KDM4E (0.45) | BRD4BRD9MAPTPOLBKDM4E | |
| SCHEMBL9726540 | 0.82 | KDM4E (0.44) | MAPTPOLBGAAKDM4EALDH1A1 | |
| SCHEMBL9726613 | 0.82 | BPTF (0.49) | BPTFBRD4BRD9KAT2BMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5098900-A | Reducing contractions in smooth muscles | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1992-03-24 | — | — | US | disclosed |
| EP-0186817-B1 | 3(2H)PYRIDAZINONE, PROCESS FOR ITS PREPARATION AND ANTI-ALLERGIC AGENT CONTAINING IT | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1989-08-02 | — | — | EP | disclosed |
| EP-0186817-A1 | 3(2H)pyridazinone, process for its preparation and anti-allergic agent containing it | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1986-07-09 | — | — | EP | disclosed |