Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BPTF | Q12830 | 2/20 | 0.49 |
| ▸ | BRD4 | O60885 | 5/20 | 0.45 |
| ▸ | BRD9 | Q9H8M2 | 3/20 | 0.45 |
| ▸ | KAT2B | Q92831 | 3/20 | 0.44 |
| ▸ | PDE9A | O76083 | 6/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | PDE5A | O76074 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9726598 | 0.90 | BPTF (0.52) | BPTFBRD4BRD9KAT2BPDE9A | |
| SCHEMBL10599611 | 0.88 | BPTF (0.47) | BPTFBRD4BRD9KAT2BKMT2A | |
| SCHEMBL9726609 | 0.86 | BPTF (0.46) | BPTFBRD4BRD9KAT2BPDE9A | |
| SCHEMBL9726613 | 0.85 | BPTF (0.49) | BPTFBRD4BRD9KAT2BPDE9A | |
| SCHEMBL9726619 | 0.85 | BRD4 (0.49) | BPTFBRD4BRD9KAT2BKMT2A | |
| SCHEMBL9726437 | 0.84 | BPTF (0.50) | BPTFBRD4BRD9KAT2BPDE9A | |
| SCHEMBL9726419 | 0.80 | PDE9A (0.61) | BPTFBRD4KAT2BPDE9ALMNA | |
| SCHEMBL10681057 | 0.79 | BPTF (0.42) | BPTFKAT2BPDE9ACNR2LMNA | |
| SCHEMBL10599280 | 0.79 | BRD4 (0.70) | BPTFBRD4BRD9KAT2BPDE9A | |
| SCHEMBL10601786 | 0.78 | BPTF (0.53) | BPTFBRD4BRD9KAT2BPDE9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5098900-A | Reducing contractions in smooth muscles | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1992-03-24 | — | — | US | claimed |
| EP-0186817-B1 | 3(2H)PYRIDAZINONE, PROCESS FOR ITS PREPARATION AND ANTI-ALLERGIC AGENT CONTAINING IT | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1989-08-02 | — | — | EP | claimed |
| EP-0186817-A1 | 3(2H)pyridazinone, process for its preparation and anti-allergic agent containing it | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1986-07-09 | — | — | EP | claimed |