Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 5/20 | 0.50 |
| ▸ | BPTF | Q12830 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | BRD9 | Q9H8M2 | 3/20 | 0.47 |
| ▸ | KAT2B | Q92831 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.42 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.42 |
| ▸ | PDE5A | O76074 | 1/20 | 0.41 |
| ▸ | F2 | P00734 | 1/20 | 0.41 |
| ▸ | F10 | P00742 | 1/20 | 0.41 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.41 |
| ▸ | F7 | P08709 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | THRB | P10828 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9726489 | 0.95 | ALDH1A1 (0.46) | BRD4BPTFMAPTKDM4EALDH1A1 | |
| SCHEMBL9726673 | 0.86 | BRD4 (0.46) | BRD4BPTFMAPTKDM4EALDH1A1 | |
| SCHEMBL9726437 | 0.85 | BPTF (0.50) | BRD4BPTFMAPTKDM4EALDH1A1 | |
| SCHEMBL9726581 | 0.83 | BRD4 (0.54) | BRD4BPTFMAPTKDM4EALDH1A1 | |
| SCHEMBL9726619 | 0.83 | BRD4 (0.49) | BRD4BPTFMAPTKDM4EALDH1A1 | |
| SCHEMBL9726665 | 0.83 | BRD4 (0.48) | BRD4BPTFMAPTKDM4EALDH1A1 | |
| SCHEMBL9726418 | 0.83 | KDM4E (0.46) | BRD4MAPTKDM4EALDH1A1BRD9 | |
| SCHEMBL9726693 | 0.82 | KDM4E (0.45) | MAPTKDM4EALDH1A1POLBPDE5A | |
| SCHEMBL9726674 | 0.81 | BRD4 (0.44) | BRD4BPTFMAPTKDM4EALDH1A1 | |
| SCHEMBL10599611 | 0.80 | BPTF (0.47) | BRD4BPTFMAPTKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5098900-A | Reducing contractions in smooth muscles | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1992-03-24 | — | — | US | disclosed |
| EP-0186817-A1 | 3(2H)pyridazinone, process for its preparation and anti-allergic agent containing it | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1986-07-09 | — | — | EP | disclosed |