Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.64 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | RORC | P51449 | 2/20 | 0.42 |
| ▸ | BCHE | P06276 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1206283 | 0.80 | HRH3 (0.64) | HRH3MAPTRORCBCHE | |
| SCHEMBL20287494 | 0.77 | HRH3 (0.72) | HRH3MAPTRORCBCHECYP1A2 | |
| Water SCHEMBL28117059 | 0.77 | HRH3 (0.65) | HRH3MAPTKDM4ERORCBCHE | |
| SCHEMBL19088665 | 0.76 | HRH3 (0.64) | HRH3LOXL2MAPTRORCBCHE | |
| SCHEMBL11529383 | 0.76 | LOXL2 (0.44) | LOXL2MAPTKDM4ECYP3A4NPSR1 | |
| SCHEMBL11402252 | 0.76 | HRH3 (0.53) | HRH3RORCBCHE | |
| SCHEMBL14640185 | 0.75 | HRH3 (0.69) | HRH3MAPTCYP1A2CYP2D6CYP2C9 | |
| SCHEMBL996084 | 0.75 | HRH3 (0.63) | HRH3MAPTBCHECYP1A2CYP2D6 | |
| SCHEMBL1204908 | 0.75 | HRH3 (0.69) | HRH3MAPTCYP3A4RORCBCHE | |
| SCHEMBL13078725 | 0.75 | HRH3 (0.69) | HRH3MAPTBCHECYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5098900-A | Reducing contractions in smooth muscles | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1992-03-24 | — | — | US | disclosed |
| EP-0186817-B1 | 3(2H)PYRIDAZINONE, PROCESS FOR ITS PREPARATION AND ANTI-ALLERGIC AGENT CONTAINING IT | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1989-08-02 | — | — | EP | disclosed |
| EP-0186817-A1 | 3(2H)pyridazinone, process for its preparation and anti-allergic agent containing it | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1986-07-09 | — | — | EP | disclosed |