Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | BPTF | Q12830 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.36 |
| ▸ | PDE9A | O76083 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 2/20 | 0.34 |
| ▸ | BCHE | P06276 | 2/20 | 0.33 |
| ▸ | PTGES | O14684 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9726683 | 0.92 | NPC1 (0.43) | NPC1RAB9AMEN1KMT2ABPTF | |
| SCHEMBL9726512 | 0.81 | BRD4 (0.47) | NPC1RAB9AMEN1KMT2ABPTF | |
| SCHEMBL9726707 | 0.71 | BRD4 (0.45) | RAB9ABPTFPDE9A | |
| SCHEMBL9726500 | 0.70 | BRD4 (0.46) | BPTFPDE9A | |
| SCHEMBL9726526 | 0.69 | BRD4 (0.44) | BPTFPDE9A | |
| SCHEMBL9726408 | 0.67 | BRD4 (0.42) | RAB9AMEN1KMT2ABPTFPDE9A | |
| SCHEMBL9726528 | 0.66 | BRD4 (0.52) | BPTFPDE9A | |
| SCHEMBL27606958 | 0.63 | POLB (0.50) | POLB | |
| SCHEMBL8928364 | 0.62 | PRSS1 (0.55) | — | |
| SCHEMBL24675198 | 0.61 | PRSS1 (0.49) | POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5098900-A | Reducing contractions in smooth muscles | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1992-03-24 | — | — | US | disclosed |
| EP-0186817-B1 | 3(2H)PYRIDAZINONE, PROCESS FOR ITS PREPARATION AND ANTI-ALLERGIC AGENT CONTAINING IT | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1989-08-02 | — | — | EP | disclosed |
| EP-0186817-A1 | 3(2H)pyridazinone, process for its preparation and anti-allergic agent containing it | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1986-07-09 | — | — | EP | disclosed |